747181
Poly(ethylene glycol)-block-poly(N-isopropylacrylamide)
α-methoxy, ω-dodecane, PEG Mn 2,000, PNIPAM Mn 24,000, PDI <1.2
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Synonym(s):
PEG-block-PNIPAM, PEG-b-polyNIPAM, PEGylated polyNIPAM, PNIPAAm
Linear Formula:
CH3(OC2H4)mC6H7NO2(C6H11NO)nH
UNSPSC Code:
12352100
NACRES:
NA.23
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General description
Poly(ethylene glycol)-b-poly(N-isopropylacrylamide) (PEG110-b-PNIPAM44) undergoes thermoresponsive micellization in water, forming micelles of varied size, structure and distribution depending on the concentration of the block copolymer.
Application
Well-defined PEG-block-PNIPAM diblock copolymers can form thermoresponsive vesicles in water and enable controlled drug release.
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Temperature-Controlled Assembly and Release from Polymer Vesicles of Poly(ethylene oxide)-block-poly(N-isopropylacrylamide)
Qin S, et al.
Advanced Materials, 18, 2905?2909-2905?2909 (2006)
Thermoresponsive micellization of poly (ethylene glycol)-b-poly (N-isopropylacrylamide) in water.
Zhang W
Macromolecules, 38(13), 5743-5747 (2005)
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