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Sigma-Aldrich

Maleimide-PEG2-succinimidyl ester

≥95%

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Synonym(s):
3-[2-[2-[[3-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]ethoxy]propanoic acid 2,5-dioxo-1-pyrrolidinyl ester, Maleimide-PEG2-NHS
Empirical Formula (Hill Notation):
C18H23N3O9
CAS Number:
955094-26-5
Molecular Weight:
425.39
MDL number:
MFCD11041137
UNSPSC Code:
12352200
PubChem Substance ID:
329765750
NACRES:
NA.22

Quality Level

100

Assay

≥95%

form

solid

reaction suitability

reaction type: Pegylations
reagent type: cross-linking reagent

mp

92-94 °C

functional group

NHS ester
maleimide

storage temp.

−20°C

SMILES string

O=C(N1CCC(NCCOCCOCCC(ON(C(CC2)=O)C2=O)=O)=O)C=CC1=O

InChI

1S/C18H23N3O9/c22-13(5-8-20-14(23)1-2-15(20)24)19-7-10-29-12-11-28-9-6-18(27)30-21-16(25)3-4-17(21)26/h1-2H,3-12H2,(H,19,22)

InChI key

TZPDZOJURBVWHS-UHFFFAOYSA-N

Related Categories

Application

Heterobifunctional crosslinker with short ethylene oxide spacer for linking amine- to sulfhydryl-containing compounds or biomolecules. Maleimide functional group will react with sulfhydryls and the succinimidyl ester group will react with amines. Spacer length is 17.6 angstroms.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Elucidating the mechanisms that controlled T cell activation requires visualization of the spatial organization of multiple proteins on the submicron scale. Here, we use stoichiometrically accurate, multiplexed, single-molecule super-resolution microscopy (DNA-PAINT) to image the nanoscale spatial architecture of the primary inhibitor
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