740705
Poly(ethylene glycol) methyl ether 2-(dodecylthiocarbonothioylthio)-2-methylpropionate
average Mn 1,100
Synonym(s):
Methoxy poly(ethylene oxide)-2-(dodecylthiocarbonothioylthio)-2-methylpropionate, PEG DDMAT macroCTA
About This Item
form
liquid
semisolid
solid
mol wt
average Mn 1,100
reaction suitability
reagent type: chemical modification reagent
reaction type: Polymerization Reactions
transition temp
Tm 22-27 °C
PDI
≤1.1
Ω-end
DDMAT
α-end
methoxy
polymer architecture
shape: linear
functionality: monofunctional
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General description
Molecular weight: PEG Average Mn ~750 kDa; n ~17
Application
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
Target Organs
Respiratory system
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Articles
Reversible addition–fragmentation chain transfer (RAFT) polymerization is rapidly moving to the forefront in construction of drug and gene delivery vehicles.
The modification of biomacromolecules, such as peptides and proteins, through the attachment of synthetic polymers has led to a new family of highly advanced biomaterials with enhanced properties.
Micro review of reversible addition/fragmentation chain transfer (RAFT) polymerization.
Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.
Protocols
We present an article about RAFT, or Reversible Addition/Fragmentation Chain Transfer, which is a form of living radical polymerization.
We presents an article featuring procedures that describe polymerization of methyl methacrylate and vinyl acetate homopolymers and a block copolymer as performed by researchers at CSIRO.
Polymerization via ATRP procedures demonstrated by Prof. Dave Haddleton's research group at the University of Warwick.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
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