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725331

Sigma-Aldrich

Iron oxide(II,III), magnetic nanoparticles solution

5 nm avg. part. size, 5 mg/mL in H2O

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Synonym(s):
Magnetic iron oxide nanocrystals, Magnetite, Superparamagnetic iron oxide nanoparticles
Empirical Formula (Hill Notation):
Fe3O4
CAS Number:
1317-61-9
Molecular Weight:
231.53
MDL number:
MFCD00011010
UNSPSC Code:
12352302
PubChem Substance ID:
329764148
NACRES:
NA.23

form

dispersion
nanoparticles

Quality Level

100

concentration

5 mg/mL in H2O

magnetization

>25 emu/g, at 4500Oe

particle size

4-6 nm (TEM)

avg. part. size

5 nm

density

1.00 g/mL at 25 °C

SMILES string

O=[Fe].O=[Fe]O[Fe]=O

InChI

1S/3Fe.4O

InChI key

SZVJSHCCFOBDDC-UHFFFAOYSA-N

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General description

Iron oxide(II,III), magnetic nanoparticles solution is a chemically stable dispersed solution with a large surface to volume ratio. Its properties include good biocompatibility, and magnetic susceptibility (χ).
Concentration 5mg/ml includes total weight nanocrystals plus ligands.

Application

Fe3O4 magnetic nanoparticles solution can be used in a variety of biomedical applications such as drug delivery. It can also be coated for immobilization of surface atoms for chelation of metal ions.

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Magnetic gamma-Fe2O3 nanoparticles coated with poly-l-cysteine for chelation of As (III), Cu (II), Cd (II), Ni (II), Pb (II) and Zn (II)
White BR, et al.
Journal of Hazardous Materials, 161(2-3), 848-853 (2009)
Magnetic resonance imaging of ultrasmall superparamagnetic iron oxide-labeled exosomes from stem cells: a new method to obtain labeled exosomes
Busato A, et al.
International journal of nanomedicine, 11(3), 2481-2481 (2016)
Magnetic nanoparticles-a review
Indira TK and Lakshmi PK
International Journal of Pharmaceutical Sciences and Nanotechnology, 3(3), 1035-1042 (2010)
Microfluidic synthesis of microfibers for magnetic-responsive controlled drug release and cell culture
Lin Y, et al.
Testing, 7(3), e33184-e33184 (2012)
Tsung-Ju Li et al.
Biomaterials, 34(32), 7873-7883 (2013-07-24)
We present an approach for synchronizing hyperthermia and thermal-responsive local drug release. The targeting probe has a magnetite nanocrystal (Fe₃O₄@PSMA) core and a polynucleotide shell that carries 5-fluorouracil (5-FU) and anti-human epidermal growth factor receptor 2 (anti-HER2) antibody for cancer
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