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719935

Sigma-Aldrich

Resomer® R 203 S, Poly(D,L-lactide)

ester terminated, Mw 18,000-28,000

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Synonym(s):
Lactide polymer, PDLLA
Linear Formula:
[C3H4O2]x[C2H2O2]y
CAS Number:
202832-99-3
UNSPSC Code:
12162002
NACRES:
NA.23

Quality Level

200

form

amorphous

mol wt

Mw 18,000-28,000

degradation timeframe

<6 months

viscosity

0.25-0.35 dL/g, 0.1 % (w/v) in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)

transition temp

Tg 46-50 °C

storage temp.

2-8°C

SMILES string

[H]OC(C(OC(C(O[R])=O)C)=O)C

InChI

1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2

InChI key

LCSKNASZPVZHEG-UHFFFAOYSA-N

Related Categories

General description

Ester terminated Poly(D,L-lactide) (PDLLA, RESOMER® ) is a copolymer of L and D-lactic acid and (or L and D lactide). The structure is highly irregular and amorphous. RESOMER® polymers are bioresorbable aliphatic polyesters comprised of a range of different ratios of lactide and glycolide monomers, PLA stereochemistries, and end-group functionalization.

Application

This biodegradable polyester is useful for the controlled release of drugs both in vitro and in vivo.

Legal Information

Product of Evonik
RADIANT is a registered trademark of Bio-Rad Laboratories, Inc.
RESOMER is a registered trademark of Evonik Rohm GmbH

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Auras RA, et al.
Poly(lactic acid): Synthesis, Structures, Properties, Processing, and Application null
Biodegradable polyesters for controlled release of trypanocidal drugs: in vitro and in vivo studies.
Lemmouchi Y, et al.
Biomaterials, 19(20), 1827-1837 (1998)

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Bioprinting for Tissue Engineering and Regenerative Medicine

In the past two decades, tissue engineering and regenerative medicine have become important interdisciplinary fields that span biology, chemistry, engineering, and medicine.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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