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715034

Sigma-Aldrich

3-(Diphenylphosphino)propionic acid

97%

Synonym(s):

(2-Carboxyethyl)diphenylphosphine, 4,4-Diphenyl-4-phosphabutanoic acid

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About This Item

Empirical Formula (Hill Notation):
C15H15O2P
CAS Number:
2848-01-3
Molecular Weight:
258.25
MDL number:
MFCD00775376
UNSPSC Code:
12352002
PubChem Substance ID:
329763337
NACRES:
NA.22

Quality Level

100

Assay

97%

form

solid

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: ligand

mp

130-134 °C

functional group

phosphine

SMILES string

OC(=O)CCP(c1ccccc1)c2ccccc2

InChI

1S/C15H15O2P/c16-15(17)11-12-18(13-7-3-1-4-8-13)14-9-5-2-6-10-14/h1-10H,11-12H2,(H,16,17)

InChI key

OTSIFUHGOBFOTH-UHFFFAOYSA-N

Application

Reactant for:
  • Organocatalytic asymmetric aziridination of imines and diazo compounds
  • Phosphine-mediated conversion of azides into diazo compounds
  • Preparation of rhodium catalysts for hydroformylation
  • Synthesis of reagents for the Mitsunobu reaction

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
SHBK0806
SHBJ2707
SHBG9440V
SHBB0517V
SHBB0517

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Dania Ahmed et al.
AMB Express, 7(1), 210-210 (2017-11-23)
Biofilm formation by pathogenic bacteria is one of the major threats in hospital related infections, hence inhibiting and eradicating biofilms has become a primary target for developing new anti-infection approaches. The present study was aimed to develop novel antibiofilm agents

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