Skip to Content
Merck
CN
All Photos(2)

Documents

Safety Information

700150

Sigma-Aldrich

(S)-Boc-5-oxopyrrolidine-2-carboxylic acid

97%

Synonym(s):

(−)-1-Boc-L-pyroglutamic acid, Boc-pyr-OH

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C10H15NO5
CAS Number:
Molecular Weight:
229.23
EC Number:
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

97%

form

powder

optical activity

[α]22/D −35.0, c = 1 in chloroform

reaction suitability

reaction type: Boc solid-phase peptide synthesis

mp

118-123 °C (dec.)

application(s)

peptide synthesis

storage temp.

−20°C

SMILES string

CC(C)(C)OC(=O)N1[C@@H](CCC1=O)C(O)=O

InChI

1S/C10H15NO5/c1-10(2,3)16-9(15)11-6(8(13)14)4-5-7(11)12/h6H,4-5H2,1-3H3,(H,13,14)/t6-/m0/s1

InChI key

MJLQPFJGZTYCMH-LURJTMIESA-N

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

新产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Qiuyu Gong et al.
Advanced science (Weinheim, Baden-Wurttemberg, Germany), 5(4), 1700664-1700664 (2018-05-04)
Previous study showed that pyroglutamate aminopeptidase 1 (PGP-1) has a relationship with the immune response in cells. However, whether PGP-1 is involved in inflammatory response in vivo and can serve as a new inflammatory cytokine are still unclear. To address
Kathrin Gnoth et al.
Alzheimer's research & therapy, 12(1), 149-149 (2020-11-16)
Amyloid β (Aβ)-directed immunotherapy has shown promising results in preclinical and early clinical Alzheimer's disease (AD) trials, but successful translation to late clinics has failed so far. Compelling evidence suggests that post-translationally modified Aβ peptides might play a decisive role

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service