Skip to Content
Merck
CN

686271

(S)-4-Chloro-α-methylbenzyl alcohol

95%

Synonym(s):

(S)-1-(4-Chlorophenyl)ethanol, (S)-4′-Chloro-1-phenylethanol

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Linear Formula:
ClC6H4CH(CH3)OH
CAS Number:
99528-42-4
Molecular Weight:
156.61
NACRES:
NA.22
PubChem Substance ID:
329761034
UNSPSC Code:
12352101
MDL number:
MFCD06797296

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

(S)-4-Chloro-α-methylbenzyl alcohol, 95%

InChI

1S/C8H9ClO/c1-6(10)7-2-4-8(9)5-3-7/h2-6,10H,1H3/t6-/m0/s1

SMILES string

C[C@H](O)c1ccc(Cl)cc1

InChI key

MVOSNPUNXINWAD-LURJTMIESA-N

assay

95%

form

liquid

optical activity

[α]20/D -48.0°, c = 1 in chloroform

refractive index

n20/D 1.544

density

1.175 g/mL at 25 °C

functional group

chloro
hydroxyl

Quality Level

100

Related Categories

Application

(S)-4-Chloro-α-methylbenzyl alcohol can be used as a chiral building block in:
  • The enantioselective synthesis of (-)-(S,S)-clemastine.
  • The enantioselective and geometrically defined synthesis of chloro methylbenzyl pinacol boronic ester via lithiation−borylation methodology.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

>230.0 °F

flash_point_c

> 110 °C

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

新产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKBN7473V
14917JH

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Stereospecific conversion of alcohols into pinacol boronic esters using lithiation-borylation methodology with pinacolborane
Roesner S, et al.
Chemical Communications (Cambridge, England), 50(31), 4053-4055 (2014)
Anne M Fournier et al.
Organic letters, 12(10), 2222-2225 (2010-04-22)
The first enantioselective synthesis of the antihistamine agent clemastine, as its (S,S)-stereoisomer, has been achieved by ether formation between a proline-derived chloroethylpyrrolidine and an enantiomerically enriched tertiary alcohol. The tertiary alcohol was formed from the carbamate derivative of alpha-methyl-p-chlorobenzyl alcohol

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service