684090
2-Aminopyridine-3-carboxamide
97%
Synonym(s):
2-Aminonicotinamide
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About This Item
Empirical Formula (Hill Notation):
C6H7N3O
CAS Number:
Molecular Weight:
137.14
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Product Name
2-Aminopyridine-3-carboxamide, 97%
InChI
1S/C6H7N3O/c7-5-4(6(8)10)2-1-3-9-5/h1-3H,(H2,7,9)(H2,8,10)
SMILES string
NC(=O)c1cccnc1N
InChI key
HTPCDVLWYUXWQR-UHFFFAOYSA-N
assay
97%
form
powder
mp
194-200 °C
functional group
amide
Quality Level
Related Categories
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Sens. 1
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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Christopher L Frank et al.
Toxicological sciences : an official journal of the Society of Toxicology, 160(1), 121-135 (2017-10-04)
Less than 1% of environmental chemicals have been evaluated for developmental neurotoxicity (DNT). Current guideline DNT studies are resource intensive and not amenable to screening large numbers of compounds for hazard. As part of evaluating a battery of more rapid
Haizhen Wang et al.
Nature, 546(7658), 426-430 (2017-06-14)
D-type cyclins (D1, D2 and D3) and their associated cyclin-dependent kinases (CDK4 and CDK6) are components of the core cell cycle machinery that drives cell proliferation. Inhibitors of CDK4 and CDK6 are currently being tested in clinical trials for patients
Joshua A Harrill et al.
Toxicology and applied pharmacology, 354, 24-39 (2018-04-08)
Medium- to high-throughput in vitro assays that recapitulate the critical processes of nervous system development have been proposed as a means to facilitate rapid testing and identification of chemicals which may affect brain development. In vivo neurodevelopment is a complex
Wen-jing Xiao et al.
Acta pharmacologica Sinica, 36(2), 259-267 (2015-01-27)
The pentose phosphate pathway (PPP) is involved in the activity of glucose-6-phosphate dehydrogenase (G6PD) and generation of NADPH, which plays a key role in drug metabolism. The aim of this study was to investigate the effects of modulation of the
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