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683965

Sigma-Aldrich

2,4-Bis(trifluoromethyl)phenylboronic acid

≥95%

Synonym(s):

(2,4-Ditrifluoromethylphenyl)boronic acid, 2,4-Bis(trifluoromethyl)benzeneboronic acid, 2,4-Di(trifluoromethyl)benzeneboronic acid

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About This Item

Empirical Formula (Hill Notation):
C8H5BF6O2
CAS Number:
Molecular Weight:
257.93
MDL number:
UNSPSC Code:
12352103
PubChem Substance ID:
NACRES:
NA.22

Assay

≥95%

form

crystals

mp

110-117 °C

SMILES string

OB(O)c1ccc(cc1C(F)(F)F)C(F)(F)F

InChI

1S/C8H5BF6O2/c10-7(11,12)4-1-2-6(9(16)17)5(3-4)8(13,14)15/h1-3,16-17H

InChI key

WLYPBMBWKYALCG-UHFFFAOYSA-N

Application

Reactant for preparation of:
  • Pyrrolo[2,3-d]pyrimidin-4-ones as corticotropin-releasing factor 1 receptor antagonists with a carbonyl-based hydrogen bonding acceptor
  • Biaryl pyrazole carboxamides as sodium channel blockers for treatment of neuropathic pain
  • Biphenylketones as dual modulators of inflammation and bone loss
  • (Biphenylyl)pyrazolecarboxamides and their voltage-gated sodium channel Nav1.7 blocking structure-activity relationship
  • N-hydroxyalkyl biphenylsulfonamides as inhibitors of bone resorption
  • 1,3,6,8a-tetraazaacenaphthylene derivatives and study of their activity as corticotropin-releasing factor-1 antagonists
  • Blue luminescent iridium phenylpyridine complexes

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

新产品

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