Skip to Content
Merck
CN
All Photos(1)

Documents

681555

Sigma-Aldrich

1-[2-[Bis(tert-butyl)phosphino]phenyl]-3,5-diphenyl-1H-pyrazole

96%

Sign Into View Organizational & Contract Pricing
All Photos(1)
Synonym(s):
TrippyPhos
Empirical Formula (Hill Notation):
C29H33N2P
CAS Number:
628333-86-8
Molecular Weight:
440.56
MDL number:
MFCD09038823
UNSPSC Code:
12352005
PubChem Substance ID:
24885641

Assay

96%

form

solid

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: ligand
reaction type: Cross Couplings

mp

138-142 °C

functional group

phosphine

SMILES string

CC(C)(C)P(c1ccccc1-n2nc(cc2-c3ccccc3)-c4ccccc4)C(C)(C)C

InChI

1S/C29H33N2P/c1-28(2,3)32(29(4,5)6)27-20-14-13-19-25(27)31-26(23-17-11-8-12-18-23)21-24(30-31)22-15-9-7-10-16-22/h7-21H,1-6H3

InChI key

JAIIBHBCNPAPPF-UHFFFAOYSA-N

Application

Catalyst in:
  • Palladium-catalyzed cross-coupling-alkyne cyclization
  • Heterocyclization of diketones
Non-proprietary ligand for palladium-catalyzed amination or aryl halides including aryl chlorides. Works best when the palladium source is Pd2(dba)3 (328774).

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H302,H315,H318,H335

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Synthesis, 1727-1727 (2003)
Tetrahedron Letters, 47, 3727-3727 (2006)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service