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67073

Sigma-Aldrich

7-Methylguanine

≥98.0% (HPLC)

Synonym(s):

2-Amino-6-hydroxy-7-methylpurine, Epiguanine

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About This Item

Empirical Formula (Hill Notation):
C6H7N5O
CAS Number:
Molecular Weight:
165.15
Beilstein:
174245
EC Number:
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥98.0% (HPLC)

impurities

≤1% guanine

SMILES string

Cn1cnc2N=C(N)NC(=O)c12

InChI

1S/C6H7N5O/c1-11-2-8-4-3(11)5(12)10-6(7)9-4/h2H,1H3,(H3,7,9,10,12)

InChI key

FZWGECJQACGGTI-UHFFFAOYSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Chie Tomikawa et al.
Nucleic acids research, 38(3), 942-957 (2009-11-26)
N(7)-methylguanine at position 46 (m(7)G46) in tRNA is produced by tRNA (m(7)G46) methyltransferase (TrmB). To clarify the role of this modification, we made a trmB gene disruptant (DeltatrmB) of Thermus thermophilus, an extreme thermophilic eubacterium. The absence of TrmB activity
H A Billson et al.
Carcinogenesis, 30(4), 615-620 (2009-01-27)
Components of human diets may influence the incidence of colorectal adenomas, by modifying exposure or susceptibility to DNA-damaging alkylating agents. To examine this hypothesis, a food frequency questionnaire was used to assess the diet of patients recruited for a case-referent
Chiung-Wen Hu et al.
Chemical research in toxicology, 25(11), 2386-2392 (2012-10-05)
Areca nut is a carcinogen to humans and has been strongly associated with oral premalignant and malignant diseases. Previous studies speculated the presence of unknown direct-acting mutagens present in aqueous extracts of areca nut. We hypothesized whether any direct-acting alkylating
S J Stocks et al.
Mutation research, 698(1-2), 18-23 (2010-03-24)
Approximately one-third of IVF cases in the UK are attributed to male factor infertility and in the majority of cases the origin of male infertility is unknown. The integrity of sperm DNA is important both for the success of assisted
Hongyu Gu et al.
The Analyst, 145(20), 6705-6712 (2020-08-20)
Terahertz wave has a good ability to identify biomolecules due to its fingerprint spectrum characteristics. However, the minimum detectable limit of terahertz technology by the conventional tablet pressing method is on the order of milligrams, which cannot meet the application

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