Quality Level
Assay
97%
form
solid
mp
99-103 °C (lit.)
SMILES string
Brc1cnc(I)nc1
InChI
1S/C4H2BrIN2/c5-3-1-7-4(6)8-2-3/h1-2H
InChI key
ZEZKXPQIDURFKA-UHFFFAOYSA-N
Related Categories
General description
5-Bromo-2-iodopyrimidine can be synthesized by reacting 5-bromo-2-chloropyrimidine with hydroiodic acid.
Application
5-Bromo-2-iodopyrimidine can be used to synthesize 5,5′-dibromo-2,2′-bipyrimidine and O,O′-dimethyl hyrtinadine A.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Find documentation for the products that you have recently purchased in the Document Library.
"One-Pot Synthesis of Diazine-Bridged Bisindoles and Concise Synthesis of the Marine Alkaloid Hyrtinadine A"
European Journal of Organic Chemistry, 2011(24), 4532- 4535 (2011)
The Journal of organic chemistry, 67(18), 6550-6552 (2002-08-31)
A high-yield synthesis was developed for the preparation of 2,2'-bipyrimidine (1) using the Ullmann coupling of 2-iodopyrimidine. The new procedure was also used for the preparation of 4,4',6,6'-tetramethyl-2,2'-bipyrimidine (2) and 5,5'-dibromo-2,2'-bipyrimidine (3).
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