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About This Item
Empirical Formula (Hill Notation):
C9H8O2
CAS Number:
Molecular Weight:
148.16
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Assay
97%
form
solid
mp
154-158 °C (lit.)
SMILES string
Oc1ccc2CCC(=O)c2c1
InChI
1S/C9H8O2/c10-7-3-1-6-2-4-9(11)8(6)5-7/h1,3,5,10H,2,4H2
InChI key
MOANRQDXNNXOLW-UHFFFAOYSA-N
Application
6-Hydroxy-1-indanone can be used in the synthesis of tetracyclic ketones intermediates during the total syntheses of (±)-frondosin C and (±)-8-epi-frondosin C. It can also be used in the synthesis of 1,4-dihydroindeno[1,2-c]pyrazoles, which can act like potent CHK-1 inhibitors, thereby inhibiting the growth of cancer cells.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Find documentation for the products that you have recently purchased in the Document Library.
"Cyanopyridyl containing 1, 4-dihydroindeno [1, 2-c] pyrazoles as potent checkpoint kinase 1 inhibitors: Improving oral biovailability"
Tong Y, et al.
Bioorganic & Medicinal Chemistry, 17(20), 5665-5670 (2007)
"Total syntheses of (?)-frondosin C and (?)-8-epi-frondosin C via a tandem anionic 5-exo dig cyclization?Claisen rearrangement sequence"
Li X. et al.
Tetrahedron, 63(09), 1899-1906 (2007)
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