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Key Documents

58920

Sigma-Aldrich

L-Isoleucine methyl ester hydrochloride

≥98.0% (AT)

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About This Item

Linear Formula:
CH3CH2CH(CH3)CH(NH2)COOCH3 · HCl
CAS Number:
Molecular Weight:
181.66
Beilstein:
3595132
EC Number:
MDL number:
UNSPSC Code:
12352200
eCl@ss:
32160406
PubChem Substance ID:

Assay

≥98.0% (AT)

optical activity

[α]20/D +27.0±1°, c = 2% in H2O

reaction suitability

reaction type: solution phase peptide synthesis

mp

96-100 °C

application(s)

peptide synthesis

SMILES string

Cl.CC[C@H](C)[C@H](N)C(=O)OC

InChI

1S/C7H15NO2.ClH/c1-4-5(2)6(8)7(9)10-3;/h5-6H,4,8H2,1-3H3;1H/t5-,6-;/m0./s1

InChI key

GGTBEWGOPAFTTH-GEMLJDPKSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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I B Rozenval'd
Tsitologiia, 32(3), 220-226 (1990-01-01)
Lysosomal inhibitors (amino acid methyl esters) and the platelet-derived growth factor stimulate the resting NIH 3T3 cells to enter the S period. Incubation of cells in the medium containing lysosomal inhibitors enhances protein accumulation and seemingly does not disrupt lysosomes.
Walter S Leal et al.
Journal of chemical ecology, 29(1), 15-25 (2003-03-22)
Three amino acid-derived compounds were identified in extracts from the pheromone glands of the scarab beetle Phyllophaga elenans, i.e., L-isoleucine methyl ester (LIME), N-formyl L-isoleucine methyl ester (For-LIME), and N-acetyl L-isoleucine methyl ester (Ac-LIME). The compounds were characterized from their
S C Alfieri et al.
Parasitology, 95 ( Pt 1), 31-41 (1987-08-01)
L-Amino acid esters, such as leucine methyl ester (Leu-OMe) can destroy intracellular as well as isolated amastigotes of Leishmania mexicana amazonensis by a mechanism which may involve ester hydrolysis by parasite enzymes. We show here that several other esters prevented
Paul S Robbins et al.
Journal of chemical ecology, 34(2), 205-214 (2008-01-24)
This study offers experimental evidence for the existence of three pheromone races of the northern genitalic form of Phyllophaga anxia: one race in which females produce and males respond mainly to L-valine methyl ester, a second producing and responding to
Yuta Kawasaki et al.
The Journal of experimental biology, 220(Pt 21), 4024-4034 (2017-09-08)
Two-day rhythms, referred to as circa'bi'dian rhythms, have been reported in humans and mosquitos. However, these rhythms only appear under constant conditions, and the functional mechanisms of 2-day rhythms were unknown. Here, we report clear circabidian rhythms of large black

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