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572640

Sigma-Aldrich

4-Methylbenzhydryl chloride, polymer-bound

100-200 mesh, extent of labeling: 1.6-2.2 mmol/g loading, 1 % cross-linked with divinylbenzene

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About This Item

MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.22

crosslinking

1 % cross-linked with divinylbenzene

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis
reactivity: nucleophile reactive

extent of labeling

1.6-2.2 mmol/g loading

particle size

100-200 mesh

Application

The benzyhydryl chloride resins are used for the attachment of amines, alcohols, sulfamates, thiols and phenols using the Fmoc strategy. These resins are an intermediate between the Merrifield resin and the trityl chloride resins in term of acid lability. The carbocation formed during the cleavage reaction is less stable than the Merrifield resin but more stable than the trityl chloride resin. The 4-Merthylbenzhydryl chloride resin is a more acid labile resin than the benzhydryl chloride resin.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

新产品

Certificates of Analysis (COA)

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