572640
4-Methylbenzhydryl chloride, polymer-bound
100-200 mesh, extent of labeling: 1.6-2.2 mmol/g loading, 1 % cross-linked with divinylbenzene
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crosslinking
1 % cross-linked with divinylbenzene
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
reactivity: nucleophile reactive
extent of labeling
1.6-2.2 mmol/g loading
particle size
100-200 mesh
Application
The benzyhydryl chloride resins are used for the attachment of amines, alcohols, sulfamates, thiols and phenols using the Fmoc strategy. These resins are an intermediate between the Merrifield resin and the trityl chloride resins in term of acid lability. The carbocation formed during the cleavage reaction is less stable than the Merrifield resin but more stable than the trityl chloride resin. The 4-Merthylbenzhydryl chloride resin is a more acid labile resin than the benzhydryl chloride resin.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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