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Sigma-Aldrich

N-(2-Aminoethyl)maleimide trifluoroacetate salt

≥98% (T), for peptide synthesis

Synonym(s):

2-Maleimidoethylamine trifluoroacetate salt

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About This Item

Empirical Formula (Hill Notation):
C6H8N2O2 · C2HF3O2
CAS Number:
146474-00-2
Molecular Weight:
254.16
MDL number:
MFCD01073617
UNSPSC Code:
12161502
PubChem Substance ID:
57651612
NACRES:
NA.22

product name

N-(2-Aminoethyl)maleimide trifluoroacetate salt, ≥95% (HPLC), ≥98% (T)

Quality Level

100

Assay

≥95% (HPLC)
≥98% (T)

form

powder

reaction suitability

reagent type: cross-linking reagent
reagent type: linker

functional group

amine
maleimide

polymer architecture

functionality: heterobifunctional

SMILES string

OC(C(F)(F)F)=O.O=C1N(CCN)C(C=C1)=O

InChI

1S/C6H8N2O2.C2HF3O2/c7-3-4-8-5(9)1-2-6(8)10;3-2(4,5)1(6)7/h1-2H,3-4,7H2;(H,6,7)

InChI key

YNHKVOGCDPODMT-UHFFFAOYSA-N

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General description

N-(2-Aminoethyl)maleimide trifluoroacetate salt is a thiol reactive cross-linking agent used in the preparation of heparin hydrogels

Application

N-(2-Aminoethyl)maleimide trifluoroacetate salt commonly utilized:
  • As a crosslinking agent to form covalent bonds between polymeric precursors
  • In the synthesis of maleimide-functionalized heparin hydrogels by introducing maleimide functional groups to molecules, enabling subsequent bioconjugation
  • In the synthesis of N-(2-{3-Iodobenzoyl}aminoethyl)maleimide and N-(2-{3-(tri-n-Butylstannyl)benzoyl}aminoethyl)maleimide
  • As a building block in the synthesis of maleimide-functionalized cymantrenyl derivatives

Other Notes

Heterobifunctional linker for introducing a maleimide function into the widely used NOSu-modified fluorescent labels.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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