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560529

Sigma-Aldrich

3,4-Methylenedioxyphenethylamine hydrochloride

98%

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Empirical Formula (Hill Notation):
C9H11NO2 · HCl
CAS Number:
Molecular Weight:
201.65
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

98%

mp

216-218 °C (lit.)

SMILES string

Cl.NCCc1ccc2OCOc2c1

InChI

1S/C9H11NO2.ClH/c10-4-3-7-1-2-8-9(5-7)12-6-11-8;/h1-2,5H,3-4,6,10H2;1H

InChI key

NDYXFQODWGEGNU-UHFFFAOYSA-N

Related Categories

General description

3,4-Methylenedioxyphenethylamine hydrochloride can be synthesized by reacting aluminum chloride, LiAlH4 and 3,4-methylenedioxyphenylacetonitrile.

Application

3,4-Methylenedioxyphenethylamine hydrochloride may be used to synthesize N-(3,4-methylenedioxyphenethyl)-2-(3-bromo-4-methoxyphenyl)acetamide.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Milica Ninković et al.
Nephrology (Carlton, Vic.), 13(1), 33-37 (2008-01-18)
The mechanism of MDMA (3,4-methylenedioxymethamphetamine)-induced toxicity is believed to be, in part, due to enhanced oxidative stress. As MDMA is eliminated via the kidney, the aim of this study was to investigate whether MDMA created conditions of oxidative stress within
J F Bagli et al.
Journal of medicinal chemistry, 19(7), 876-882 (1976-07-01)
Synthesis of a series of thienylethanolamines having varying substituents on the thiophene ring and on the nitrogen atom is described using the general procedure reported earlier. In the determination of their pharmacological profile, some of the derivatives showed marked antihypertensive
An aryne route to laureline, and related topics.
Gibson MS, et al.
J. Chem. Soc. Sect. C, 16, 2234-2238 (1970)
D J De Silva et al.
Neuroscience, 134(4), 1363-1375 (2005-08-02)
Substituted amphetamines such as p-chloroamphetamine and the abused drug methylenedioxymethamphetamine cause selective destruction of serotonin axons in rats, by unknown mechanisms. Since some serotonin neurones also express neuronal nitric oxide synthase, which has been implicated in neurotoxicity, the present study
Jan G Bruhn et al.
Journal of psychoactive drugs, 40(2), 219-222 (2008-08-30)
Human interest in psychoactive phenethylamines is known from the use of mescaline-containing cacti and designer drugs such as Ecstasy. From the alkaloid composition of cacti we hypothesized that substances resembling Ecstasy might occur naturally. In this article we show that

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