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556289

Sigma-Aldrich

Methyl picolinate

99%

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About This Item

Empirical Formula (Hill Notation):
C7H7NO2
CAS Number:
Molecular Weight:
137.14
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

99%

refractive index

n20/D 1.521 (lit.)

bp

95 °C/1 mmHg (lit.)

density

1.137 g/mL at 25 °C (lit.)

SMILES string

COC(=O)c1ccccn1

InChI

1S/C7H7NO2/c1-10-7(9)6-4-2-3-5-8-6/h2-5H,1H3

InChI key

NMMIHXMBOZYNET-UHFFFAOYSA-N

General description

Methyl picolinate (MP) exists in two conformers i.e s-trans and s-cis. Molecular structure of these forms has been investigated by gas electron diffraction.

Application

Methyl picolinate may be used in the synthesis of:
  • 3-substituted-imidazo[1,5-α]pyridines
  • N-benzylpicolinamide
  • 3-phenylsubstituted imidazo[1,5-α]pyridines
  • pyrimine
  • 4,6-dipyridylpyrimidine

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

217.4 °F - closed cup

Flash Point(C)

103 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Peter J Steel
Molecules (Basel, Switzerland), 9(6), 440-448 (2007-11-17)
The syntheses of representative examples of five classes of new heterocyclic ligands are described. These include N,N'-chelating bis-heterocycles, binucleating ligands, cyclometallated compounds, chiral ligands and a family of polyheteroaryl-linked arenes.
Microwave-assisted organic synthesis of 3-substituted-imidazo [1, 5-a] pyridines.
Arvapalli VS, et al.
Tetrahedron Letters, 51(2), 284-286 (2010)
Structure determination of methyl nicotinate and methyl picolinate by gas electron diffraction combined with ab initio calculations.
Kiyono H, et al.
The Journal of Physical Chemistry A, 102(8), 1405-1411 (1998)
Mariétou F Paye et al.
Analytical biochemistry, 549, 80-90 (2018-03-20)
Research involving α/β hydrolases, including α-amino acid ester hydrolase and cocaine esterase, has been limited by the lack of an online high throughput screening assay. The development of a high throughput screening assay capable of detecting α/β hydrolase activity toward
Isolation, Characterization, and Synthesis of Pyrimine, an Iron (II)-Binding Agent from Pseudomonas GH*.
Shiman R and Neilands JB.
Biochemistry, 4(10), 2233-2236 (1965)

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