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Safety Information

555932

Sigma-Aldrich

2-Methoxy-4-nitrobenzenesulfonyl chloride

96%

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About This Item

Linear Formula:
CH3OC6H3(NO2)SO2Cl
CAS Number:
Molecular Weight:
251.64
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:

Assay

96%

form

solid

mp

90-95 °C (lit.)

SMILES string

COc1cc(ccc1S(Cl)(=O)=O)[N+]([O-])=O

InChI

1S/C7H6ClNO5S/c1-14-6-4-5(9(10)11)2-3-7(6)15(8,12)13/h2-4H,1H3

InChI key

QECYXMKYZQXEHM-UHFFFAOYSA-N

General description

2-Methoxy-4-nitrobenzenesulfonyl chloride [4-(chlorosulphonyl)-3-methoxynitrobenzene] may be used to synthesize 2-methoxy-4-nitro-N-o-tolyl-benzenesulfonamide.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Harshani R Lawrence et al.
Bioorganic & medicinal chemistry, 18(15), 5576-5592 (2010-07-14)
Screening of the NCI Diversity Set-1 identified PI-083 (NSC-45382) a proteasome inhibitor selective for cancer over normal cells. Focused libraries of novel compounds based on PI-083 chloronaphthoquinone and sulfonamide moieties were synthesized to gain a better understanding of the structure-activity

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