55083
8-Hydroxy-2-quinolinecarboxaldehyde
≥98.0% (GC)
Synonym(s):
2-Formyl-8-hydroxyquinoline, 2-Formyl-8-quinolinol, 8-Hydroxyquinoline-2-aldehyde
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About This Item
Empirical Formula (Hill Notation):
C10H7NO2
CAS Number:
Molecular Weight:
173.17
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
127519
Assay:
≥98.0% (GC)
Form:
solid
InChI
1S/C10H7NO2/c12-6-8-5-4-7-2-1-3-9(13)10(7)11-8/h1-6,13H
SMILES string
Oc1cccc2ccc(C=O)nc12
InChI key
SLBPIHCMXPQAIQ-UHFFFAOYSA-N
assay
≥98.0% (GC)
form
solid
mp
97-100 °C
functional group
aldehyde
Quality Level
General description
8-Hydroxy-2-quinolinecarboxaldehyde can be prepared from 2-methylquinolin-8-ol via oxidation using selenium dioxide.
Application
8-Hydroxy-2-quinolinecarboxaldehyde (8-hydroxyquinoline-2-carbaldehyde) may be used in the preparation of:
- 8-hydroxy-2-quinoline-1-aminopyrene by Schiff-base reaction with 1-aminopyrene
- (E)-2-((2-(pyridin-2-yl)hydrazono)methyl)quinolin-8-ol by coupling with 2-hydrazinopyridine
- 8-hydroxyquinoline-2-carbaldehyde oxime
- 2-[(8-Hydroxyquinoline)-2-methylaminoethyl]-β-D-glucopyranoside
Other Notes
Building block for the synthesis of complexing agents
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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S. Sugata et al.
Chemical & Pharmaceutical Bulletin, 35, 2623-2623 (1987)
Saptarshi Ghosh et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 188, 252-257 (2017-07-21)
The present work reports detailed photophysics of a coumarin based Schiff base, namely, (E)-7-(((8-hydroxyquinolin-2-yl)methylene)amino)-4-methyl-2H-chromen-2-one (HMC) in different solvents of varying polarity exploiting steady state absorption, fluorescence and time resolved fluorescence spectroscopy. The dominant photophysical features of HMC are discussed in
A turn-on Schiff-base fluorescence sensor for Mg 2+ ion and its practical application.
Kao MH, et al.
Journal of Luminescence, 169, 156-160 (2016)
S-shaped decanuclear heterometallic [Ni8Ln2] complexes [Ln (iii)= Gd, Tb, Dy and Ho]: theoretical modeling of the magnetic properties of the gadolinium analogue.
Hossain S, et al.
Dalton Transactions, 43(26), 10164-10174 (2014)
Soluble sugar-based quinoline derivatives as new antioxidant modulators of metal-induced amyloid aggregation.
Oliveri V, et al.
Inorganic Chemistry, 54(6), 2591-2602 (2015)
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