549762
Ethyl 6,8-dichlorooctanoate
95%
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Linear Formula:
CH3CH2OCO(CH2)4CH(Cl)(CH2)2Cl
CAS Number:
Molecular Weight:
241.15
UNSPSC Code:
12352100
PubChem Substance ID:
EC Number:
435-080-1
MDL number:
InChI key
RFYDWSNYTVVKBR-UHFFFAOYSA-N
InChI
1S/C10H18Cl2O2/c1-2-14-10(13)6-4-3-5-9(12)7-8-11/h9H,2-8H2,1H3
SMILES string
CCOC(=O)CCCCC(Cl)CCCl
assay
95%
refractive index
n20/D 1.462 (lit.)
density
1.107 g/mL at 25 °C (lit.)
Application
Ethyl 6,8-dichlorooctanoate may be used as a starting material in the synthesis of 6-selenolipoic acid and α-lipoic acid derivatives, which show potent anticancer activity.
It may also be used as a starting material to synthesize:
It may also be used as a starting material to synthesize:
- 6,8-Dibenzylmercaptooctanoic acid, an intermediate for the preparation of DL-α-lipoic acid.
- Ethyl 5,7-dichloroheptanoate, an intermediate for the preparation of DL-1,2-dithiolane-3-butyric acid.
- 7-Bromo-1,3-dichloroheptane, an intermediate for the preparation of DL-12-dithiolane-3-butanesulfonamide.
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 2 - Skin Sens. 1
Storage Class
10 - Combustible liquids
wgk
WGK 2
flash_point_f
230.0 °F - closed cup
flash_point_c
110 °C - closed cup
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Syntheses of DL-a-lipoic acid.
Reed LJ and Niu CI.
Journal of the American Chemical Society, 77(2), 416-419 (1955)
Synthesis of DL-1, 2-Dithiolane-3-caproic Acid and DL-1, 2-Dithiolane-3-butyric Acid, Homologs of a-Lipoic Acid.
Thomas RC and Reed LJ.
Journal of the American Chemical Society, 78(23), 6151-6153 (1956)
Synthesis of some monoselenolipoic acid derivatives and their biological evaluation as anticancer agents.
Xu F, et al.
J. Chem. Res. (M), 37(5), 311-314 (2013)
Synthesis of DL-1, 2-Dithiolane-3-butanesulfonamide, an Analog of a-Lipoic Acid.
Thomas RC and Reed LJ.
Journal of the American Chemical Society, 78(23), 6150-6151 (1956)
Shi-Jie Zhang et al.
Bioorganic & medicinal chemistry letters, 20(10), 3078-3083 (2010-04-21)
alpha-Lipoic acid derivatives were synthesized and evaluated for their in vitro anticancer activities against NCI-460, HO-8910, KB, BEL-7402, and PC-3 cell lines. The results, for most compounds exhibited dose-dependent inhibitory property and several compounds had good inhibitions at the dose
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service