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Safety Information

545287

Sigma-Aldrich

Ethyl trans-2-hydroxycinnamate

97%

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About This Item

Linear Formula:
C6H4(OH)CH=CHCO2C2H5
CAS Number:
Molecular Weight:
192.21
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:

Assay

97%

mp

84-87 °C (lit.)

SMILES string

[H]\C(=C(\[H])c1ccccc1O)C(=O)OCC

InChI

1S/C11H12O3/c1-2-14-11(13)8-7-9-5-3-4-6-10(9)12/h3-8,12H,2H2,1H3/b8-7+

InChI key

SRBYHEKXHQYMRN-BQYQJAHWSA-N

General description

Ethyl trans-2-hydroxycinnamate is an o-hydroxy cinnmate ester derivative.

Application

Ethyl trans-2-hydroxycinnamate [(E)-ethyl 3-(2-hydroxyphenyl) acrylate] may be used to prepare 4-phenyl-2H-chromen-2-one, a 4-aryl coumarin derivative.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Synthesis of 4-arylcoumarins via palladium-catalyzed arylation/cyclization of ortho-hydroxylcinnamates with diaryliodonium salts.
Yang Y, et al.
Tetrahedron Letters, 56(24), 3809-3812 (2015)

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