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parameter
40-60 °C optimum reaction temp.
Application
Used for chemoenzymatic synthesis of 3-hydroxypyrrolidines and 4-(silyloxy)-2-oxopyrrolidines with two stereogenic centers.
Other Notes
This product has been replaced by L4777-SIGMA | Lipase acrylic resin from Candida antarctica ≥5,000 U/g, recombinant, expressed in Aspergillus niger
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Víctor M. Sánchez et al.
The Journal of organic chemistry, 64(5), 1464-1470 (2001-10-25)
Aminolyses of racemic and prochiral 3-hydroxyesters with racemic amines are effectively catalyzed by Candida antarctica lipase. In these processes, the simultaneous resolution of the ester and the amine, or the corresponding asymmetrization-resolution, takes place. In all cases, the high enantioselectivity
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