All Photos(1)
Synonym(s):
2-Phenylethyl-N,N-dimethylamine, Dimethyl(2-phenylethyl)amine, N,N-Dimethyl-β-phenethylamine, N,N-Dimethyl-2-phenylethylamine, N,N-Dimethylbenzeneethanamine, N,N-Dimethylphenylethylamine, N-(2-Phenylethyl)dimethylamine, N-Phenethyldimethylamine, [(Dimethylamino)ethyl]benzene
Linear Formula:
C6H5CH2CH2N(CH3)2
CAS Number:
Molecular Weight:
149.23
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
Quality Level
Assay
98%
refractive index
n20/D 1.502 (lit.)
bp
207-212 °C (lit.)
density
0.89 g/mL at 25 °C (lit.)
SMILES string
CN(C)CCc1ccccc1
InChI
1S/C10H15N/c1-11(2)9-8-10-6-4-3-5-7-10/h3-7H,8-9H2,1-2H3
InChI key
TXOFSCODFRHERQ-UHFFFAOYSA-N
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
WGK
WGK 3
Flash Point(F)
159.8 °F
Flash Point(C)
71 °C
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
监管及禁止进口产品
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H Shinotoh et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 28(6), 1006-1011 (1987-06-01)
Carbon-11-labeled N,N-dimethylphenylethylamine ([11C]DMPEA) was synthesized by the reaction of N-methylphenylethylamine with [11C]methyl iodide. This newly synthesized radiotracer was developed for the purpose of in vivo measurement of monoamine oxidase-B activity in the brain using a metabolic trapping method. Initially, biodistribution
R D Schoenwald et al.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 14(3), 253-262 (1998-07-22)
Acini cells were obtained from the lacrimal gland of the white New Zealand rabbit. Following isolation and purification, the cells were used to study the uptake of N,N'-dimethyl-2-phenylethylamine HCl (AF2975), which was found to be sodium- and proton-independent, but energy-dependent.
O Inoue et al.
Journal of neurochemistry, 44(1), 210-216 (1985-01-01)
N-[methyl-14C]N,N-dimethylphenylethylamine (DMPEA) was synthesized and its availability as a selective radiotracer for in vivo measurement of mouse brain monoamine oxidase (MAO) activity was examined. Relatively high incorporation of labelled DMPEA into brain (about 10% of the injected dose/per gram of
S Shirolkar et al.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 11(1), 41-47 (1995-01-01)
In an effort to develop a long-term topically active tear stimulant, it was important to determine if tolerance developed following the repeated instillation of N,N-Dimethyl-2-phenylethylamine hydrochloride (AF2975) to the albino rabbit eye. New Zealand white rabbits were administered AF2975 (0.15%)
R D Schoenwald et al.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 13(2), 151-161 (1997-04-01)
Fourteen dry eye volunteers placed one to two drops of 0.15% AF2975 (N,N-dimethyl-2-phenylethylamine HCl) in one eye and the vehicle in their other eye four times a day for 21 days. AF2975 is a sigma agonist known to stimulate the
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