519707
8-(Tosylamino)quinoline
97%
Synonym(s):
N-(8-Quinolyl)-p-toluenesulfonamide
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About This Item
Empirical Formula (Hill Notation):
C16H14N2O2S
CAS Number:
Molecular Weight:
298.36
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
264159
Assay:
97%
Form:
solid
InChI
1S/C16H14N2O2S/c1-12-7-9-14(10-8-12)21(19,20)18-15-6-2-4-13-5-3-11-17-16(13)15/h2-11,18H,1H3
SMILES string
Cc1ccc(cc1)S(=O)(=O)Nc2cccc3cccnc23
InChI key
ZSMKPYXVUIWTCT-UHFFFAOYSA-N
assay
97%
form
solid
mp
154-158 °C (lit.)
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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E D Gol'dberg et al.
Klinicheskaia laboratornaia diagnostika, (3)(3), 25-27 (1993-05-01)
A method for cytochemical detection of zinc in peripheral blood granulocytes with selective reaction of 8-(p-toluenesulfonyl amino)-quinoline was developed. Zinc levels in granular leukocytes were found reduced in chronic myeloleukemia and elevated in leukemoid reactions. The method may be used
V D Bovt et al.
Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 47(3), 54-57 (2001-08-25)
Alcohol dependence development is accompanied by zinc content decrease in the hippocampus. Young age, repeated physical loads and immobilization are factors, that promote such changes development in more expressed degree.
E D Gol'dberg et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (4)(4), 43-45 (1991-07-01)
The dynamics of changes of the Zn content in the pancreatic islets of rabbits after dithizon injection was studied. The amount of this metal in the islets reduced due to destruction of the cells and under the effect of high
V A Ieshchenko et al.
Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 47(2), 66-69 (2001-06-08)
Zinc content in pancreatic islet cells and hippocampus was studied with the aid of highly sensitive selective cytochemical reaction of 8-(p-toluensulfonylamino)-quinoline. It was shown that the factors stimulating B-insulocyte secretory activity induced the decrease of this metal concentrations in the
E D Gol'dberg et al.
Biulleten' eksperimental'noi biologii i meditsiny, 111(2), 135-137 (1991-02-01)
The injections of diabetogenic drugs to rabbits induced a decrease in zinc and calcium content in B insulocytes dependent on the degree of these cells damage and hyperglycemia. The content of these metals in A insulocytes was not significantly altered
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