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Merck
CN

51030

Guanine hydrochloride

≥99.0%

Synonym(s):

2-Amino-6-hydroxypurine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C5H5N5O · HCl
CAS Number:
Molecular Weight:
187.59
UNSPSC Code:
12352005
NACRES:
NA.22
PubChem Substance ID:
EC Number:
211-235-5
Beilstein/REAXYS Number:
4159901
MDL number:
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Product Name

Guanine hydrochloride, ≥99.0%

InChI key

IBAOFQIOOBQLHE-UHFFFAOYSA-N

InChI

1S/C5H5N5O.ClH/c6-5-9-3-2(4(11)10-5)7-1-8-3;/h1H,(H4,6,7,8,9,10,11);1H

SMILES string

Cl.NC1=Nc2[nH]cnc2C(=O)N1

assay

≥99.0%

form

powder

ign. residue

≤0.05%

loss

≤3.0% loss on drying

mp

≥300 °C

storage temp.

2-8°C

Quality Level

Application

Guanine hydrochloride may be used in the synthesis of Na10[Pt2(μ-PO4)4(C5H3N5O)2].22H2O.

General description

Guanine hydrochloride is the hydrochloride salt of the purine base, guanine. It is a component of basal medium.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Dhanashree Selvan et al.
ACS catalysis, 9(7), 5847-5859 (2019-07-26)
We report the construction of an artificial hydrogenase (ArH) by reengineering a Cu storage protein (Cspl) into a Ni-binding protein (NBP) employing rational metalloprotein design. The hypothesis driven design approach involved deleting existing Cu sites of Csp1 and identification of
Synthesis and X-ray structure of Na10[Pt2(?-PO4)4(C5H3N5O)2].22H2O, a complex with doubly deprotonated guanine anions coordinated to diplatinum(III).
El-Mehdawi R, et al.
Inorganic Chemistry, 25(20), 3714-3716 (1986)
The influence of magnesium on cell division. V. The effect of magnesium on the growth of bacteria in chemically-defined media of varying complexity.
M WEBB
Journal of general microbiology, 5(3), 485-495 (1951-08-01)
The estimation of guanine and xanthine.
Hitchings GH.
The Journal of Biological Chemistry, 139(2), 843-854 (1941)
Kamila Mustafina et al.
ACS synthetic biology, 9(1), 19-25 (2019-12-11)
Self-cleaving ribozymes engineered to be activated or inhibited by a small molecule binding to an RNA aptamer inserted within a ribozyme (aptazymes) have proven to be useful for controlling gene expression in living cells. In mammalian cells, an aptazyme embedded

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