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49605

Sigma-Aldrich

L-Glutamic acid hemimagnesium salt tetrahydrate

≥98.0% (NT)

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Synonym(s):
Magnesium L-glutamate
Empirical Formula (Hill Notation):
C10H16MgN2O8 · 4H2O
CAS Number:
18543-68-5
Molecular Weight:
388.61
EC Number:
242-905-5
MDL number:
MFCD00150929
UNSPSC Code:
12352209
PubChem Substance ID:
57651208
NACRES:
NA.22

Quality Level

200

Assay

≥98.0% (NT)

form

solid

reaction suitability

reaction type: solution phase peptide synthesis

application(s)

peptide synthesis

SMILES string

O.O.O.O.N[C@@H](CCC(=O)O[Mg]OC(=O)CC[C@H](N)C(O)=O)C(O)=O

InChI

1S/2C5H9NO4.Mg.4H2O/c2*6-3(5(9)10)1-2-4(7)8;;;;;/h2*3H,1-2,6H2,(H,7,8)(H,9,10);;4*1H2/q;;+2;;;;/p-2/t2*3-;;;;;/m00...../s1

InChI key

ZWCGDRSVJYJGFY-GYDBBPQESA-L

Related Categories

General description

L-Glutamic acid hemimagnesium salt tetrahydrate is commonly known as Magnesium L-glutamate. It donates magnesium ions necessary for effective protein synthesis.

Application

L-Glutamic acid hemimagnesium salt tetrahydrate is a magnesium transfer agent/carrier. It can also be used in the preparation of S30A buffer solution.

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Synthesis and antiarrhythmic activity of new biologically active potassium and magnesium donors.
Berlyand A S, et al.
Pharmaceutical Chemistry Journal, 41(12), 634-637 (2007)
Synthesis of 2.3 mg/ml of protein with an all Escherichia coli cell-free transcription?translation system.
Caschera F and Noireaux V
Biochimie, 99, 162-168 (2014)
Quantum-mechanical calculations and spectroscopic characteristics of magnesium glutamate?glycine and magnesium glutamate?arginine.
Marcoin W, et al.
Journal of Molecular Structure, 792, 186-193 (2006)
Toshiki Akui et al.
iScience, 24(8), 102859-102859 (2021-08-14)
Biochemical systems in living cells have their optimum concentration ratio among each constituent element to maintain their functionality. However, in the case of the biochemical system with complex interactions and feedbacks among elements, their activity as a system greatly changes
Efficient incorporation of unnatural amino acids into proteins with a robust cell-free system
W Gao
Methods and Protocols, 2, 16-16 (2019)
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