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Merck
CN

47649

Formaldehyde dimethyl acetal

for Grignard reactions, ≥99.0% (GC)

Synonym(s):

Dimethoxymethane, Methylal

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About This Item

Linear Formula:
CH2(OCH3)2
CAS Number:
Molecular Weight:
76.09
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
203-714-2
Beilstein/REAXYS Number:
1697025
MDL number:
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Product Name

Formaldehyde dimethyl acetal, for Grignard reactions, ≥99.0% (GC)

InChI key

NKDDWNXOKDWJAK-UHFFFAOYSA-N

InChI

1S/C3H8O2/c1-4-3-5-2/h3H2,1-2H3

SMILES string

COCOC

assay

≥99.0% (GC)

reaction suitability

reaction type: Grignard Reaction

impurities

≤0.2% water

density

0.860 g/mL at 20 °C (lit.)

functional group

acetal
ether

Quality Level

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Application

Formaldehyde dimethyl acetal may be used in the following studies:
  • Synthesis of methoxymethyl (MOM) ethers.
  • As an external cross-linker to form microporous polymers.
  • Dehydration of biological samples for scanning electron microscopy (SEM).

General description

Formaldehyde dimethyl acetal (FDA, FDMA, FADMA, dimethoxymethane, DMM, methylal) is a biodegradable dimethyl acetal. It has been synthesized by condensing formaldehyde with methanol in the presence of acid catalyst. It is ampiphilic in nature with low viscosity, surface tension and boiling point. It is a flammable, highly volatile solvent with excellent dissolving power. It is reported to form trimethylorthoformate by anodic methoxylation in basic methanol.

pictograms

Flame

signalword

Danger

hcodes

Hazard Classifications

Flam. Liq. 2

supp_hazards

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

-0.4 °F - closed cup

flash_point_c

-18 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves

Regulatory Information

危险化学品
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Electrosynthesis of trimethylorthoformate on BDD electrodes.
Fardel R, et al.
J. Appl. Electrochem., 36(2), 249-253 (2006)
Calceolariaceae: floral development and systematic implications.
Mayr EM and Weber A.
American Journal of Botany, 93(3), 327-343 (2006)
Purification and dehydration of methylal by pervaporation.
Carretier E, et al.
Journal of Membrane Science , 217(1), 159-171 (2003)
A new strategy to microporous polymers: knitting rigid aromatic building blocks by external cross-linker.
Li B, et al.
Macromolecules, 44(8), 2410-2414 (2011)
An efficient protocol for the preparation of MOM ethers and their deprotection using zirconium (IV) chloride.
Sharma GVM, et al.
Tetrahedron Letters, 45(50), 9229-9232 (2004)

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