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Merck
CN

47634

Fmoc-Met-OH

≥98.0% (HPLC), for peptide synthesis

Synonym(s):

Fmoc-L-methionine

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About This Item

Empirical Formula (Hill Notation):
C20H21NO4S
CAS Number:
71989-28-1
Molecular Weight:
371.45
NACRES:
NA.26
PubChem Substance ID:
57651052
UNSPSC Code:
12352209
EC Number:
276-258-5
MDL number:
MFCD00037134
Beilstein/REAXYS Number:
4300266

Key Documents

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Product Name

Fmoc-Met-OH, ≥98.0% (HPLC)

InChI key

BUBGAUHBELNDEW-SFHVURJKSA-N

InChI

1S/C20H21NO4S/c1-26-11-10-18(19(22)23)21-20(24)25-12-17-15-8-4-2-6-13(15)14-7-3-5-9-16(14)17/h2-9,17-18H,10-12H2,1H3,(H,21,24)(H,22,23)/t18-/m0/s1

SMILES string

CSCC[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O

assay

≥98.0% (HPLC)

optical activity

[α]20/D -29.5±1.5°, c = 1% in DMF

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

mp

121-123 °C (lit.)

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-8°C

Quality Level

100

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Related Categories

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF6888V
BCCK7455
BCCK8316
BCCH0815
BCCJ3290

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Carolyn C Woodroofe et al.
Chembiochem : a European journal of chemical biology, 21(4), 508-516 (2019-08-01)
The reversible oxidation of methionine residues in proteins has emerged as a biologically important post-translational modification. However, detection and quantitation of methionine sulfoxide in proteins is difficult. Our aim is to develop a method for specifically derivatizing methionine sulfoxide residues.
Dennis Kubiczek et al.
Macromolecular bioscience, 20(4), e2000005-e2000005 (2020-02-28)
The pathogenic yeast Candida auris has received increasing attention due to its ability to cause fatal infections, its resistance toward important fungicides, and its ability to persist on surfaces including medical devices in hospitals. To brace health care systems for
Marcus Pickhardt et al.
Current Alzheimer research, 14(7), 742-752 (2017-02-06)
Anti-aggregation drugs play an important role in therapeutic approaches for Alzheimer's disease. We have previously developed a number of compounds that are able to inhibit the pathological aggregation of Tau protein. One common obstacle to application is the limited penetration
Gizella Csire et al.
Journal of inorganic biochemistry, 170, 195-201 (2017-03-07)
The prion protein (PrP) is a membrane-anchored cell surface glycoprotein containing 231 amino acids. It has been associated with a group of neurodegenerative disorders. Copper(II) interaction with the Human Prion 103-112 fragment and its mutants has been studied with various
Gizella Csire et al.
Journal of inorganic biochemistry, 203, 110927-110927 (2019-12-07)
Interaction of copper(II) and nickel(II) ions with the Ac-PHAAAGTHSMKHM-NH2 tridecapeptide containing the His85, His96 and His111 binding sites of human prion protein has been studied by various techniques. pH-potentiometry, UV-Vis and circular dichroism spectroscopy were applied to study the stoichiometry
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