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47561

Sigma-Aldrich

Fmoc-Trp(Boc)-OH

≥97.0% (HPLC), for peptide synthesis

Synonym(s):

Nα-Fmoc-N(in)-Boc-L-tryptophan, N(in)-Boc-Nα-Fmoc-L-tryptophan

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1 VIAL
CN¥864.54
5 X 1 VIAL
CN¥3,208.78

CN¥864.54

Available to ship onApril 27, 2025Details

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1 VIAL
CN¥864.54
5 X 1 VIAL
CN¥3,208.78

About This Item

Empirical Formula (Hill Notation):
C31H30N2O6
CAS Number:
143824-78-6
Molecular Weight:
526.58
Beilstein:
7698009
MDL number:
MFCD00153366
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
57651011
NACRES:
NA.26

CN¥864.54

Available to ship onApril 27, 2025Details

Request a Bulk Order

Product Name

Fmoc-Trp(Boc)-OH, ≥97.0% (HPLC)

Quality Level

100

Assay

≥97.0% (HPLC)

form

solid

optical activity

[α]20/D −21±2°, c = 1% in DMF

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

application(s)

peptide synthesis

functional group

Boc
Fmoc

storage temp.

2-8°C

SMILES string

CC(C)(C)OC(=O)n1cc(C[C@H](NC(=O)OCC2c3ccccc3-c4ccccc24)C(O)=O)c5ccccc15

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胰蛋白酶原 来源于牛胰腺 essentially salt-free, lyophilized powder, ≥10,000 BAEE units/mg protein (E1%/280, after activation to trypsin)

T1143

胰蛋白酶原 来源于牛胰腺

form

lyophilized powder

form

powder

form

powder

form

essentially salt-free, lyophilized powder

mol wt

16,951 Da by calculation

mol wt

44287 Da by calculation, ~45 kDa

mol wt

1296 Da by calculation (Average Mass)

mol wt

23,981 Da by calculation

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

packaging

vial of ~60 nmol

packaging

vial of 25 mg

packaging

-

packaging

-

Application

Fmoc-Trp(Boc)-OH can be used for the synthesis of analogs of glucagon-like peptide-1 (GLP-1) for the treatment of type 2 diabetes[1] and various peptides by Fmoc solid phase peptide synthesis (SPPS).[2][3]

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves
  • Specification Sheet

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    Certificates of Analysis (COA)

    Lot/Batch Number
    BCCN1815
    BCCL3889
    BCCM1680
    BCCJ0705
    BCCG9287

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    Potent derivatives of glucagon-like peptide-1 with pharmacokinetic properties suitable for once daily administration.
    Knudsen LB, et al.
    Journal of Medicinal Chemistry, 43(9), 1664-1669 (2000)
    Taru Dube et al.
    Amino acids, 49(5), 975-993 (2017-03-12)
    Surging reports of peptide-based nanosystems and their growing potency in terms of biological utility demand for the search of newer and simpler peptide-based systems that could serve as smart templates for the development of self-assembled nanostructures. Use of simple amino
    Severin J Sigg et al.
    Biomacromolecules, 17(3), 935-945 (2016-02-13)
    Ever more emerging combined treatments exploiting synergistic effects of drug combinations demand smart, responsive codelivery carriers to reveal their full potential. In this study, a multifunctional stimuli-responsive amphiphilic peptide was designed and synthesized to self-assemble into nanoparticles capable of co-bearing
    Limiting racemization and aspartimide formation in microwave-enhanced Fmoc solid phase peptide synthesis.
    Palasek SA, et al.
    Journal of Peptide Science, 13(3), 143-148 (2007)
    Shabnam Tarvirdipour et al.
    Soft matter, 16(6), 1678-1691 (2020-01-23)
    To overcome the low efficiency and cytotoxicity associated with most non-viral DNA delivery systems we developed a purely peptidic self-assembling system that is able to entrap single- and double-stranded DNA of up to 100 nucleotides in length. (HR)3gT peptide design
    View All Related Papers

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