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About This Item
Linear Formula:
CH3CH(OH)CH(NH2)CH2OH
CAS Number:
Molecular Weight:
105.14
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352209
MDL number:
Beilstein/REAXYS Number:
6130524
Product Name
L-Threoninol, 97%
InChI
1S/C4H11NO2/c1-3(7)4(5)2-6/h3-4,6-7H,2,5H2,1H3/t3-,4-/m1/s1
SMILES string
C[C@@H](O)[C@H](N)CO
InChI key
MUVQIIBPDFTEKM-QWWZWVQMSA-N
assay
97%
form
solid
optical activity
[α]20/D −4.2°, c = 1% in H2O
reaction suitability
reaction type: solution phase peptide synthesis
mp
49-54 °C (lit.)
application(s)
peptide synthesis
Quality Level
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Application
L-Threoninol can be used as artificial abasic nucleoside in the synthesis and modification of oligodeoxynucleotide and can also be utilized to synthesize pyrene-L-threoninyl analogues.
General description
L-Threoninol also known as (2R,3R)-2-Amino-1,3-butanediol, is an amino alcohol, which is commonly used in solution phase peptide synthesis.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Potent triple helix stabilization by 5?, 3?-modified triplex-forming oligonucleotides
N Ben Gaied
Chembiochem, 10, 1839-1851 (2009)
Synthesis and properties of an oligonucleotide modified with an acridine derivative at the artificial abasic site
K Fukui
Bioconjugate Chemistry, 7, 349-355 (1996)
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