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469963

Sigma-Aldrich

L-Threoninol

97%, for peptide synthesis

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Synonym(s):
(2R,3R)-2-Amino-1,3-butanediol
Linear Formula:
CH3CH(OH)CH(NH2)CH2OH
CAS Number:
3228-51-1
Molecular Weight:
105.14
Beilstein:
6130524
MDL number:
MFCD00191173
UNSPSC Code:
12352209
PubChem Substance ID:
24870627
NACRES:
NA.22

Quality Level

100

Assay

97%

form

solid

optical activity

[α]20/D −4.2°, c = 1% in H2O

reaction suitability

reaction type: solution phase peptide synthesis

mp

49-54 °C (lit.)

application(s)

peptide synthesis

SMILES string

C[C@@H](O)[C@H](N)CO

InChI

1S/C4H11NO2/c1-3(7)4(5)2-6/h3-4,6-7H,2,5H2,1H3/t3-,4-/m1/s1

InChI key

MUVQIIBPDFTEKM-QWWZWVQMSA-N

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General description

L-Threoninol also known as (2R,3R)-2-Amino-1,3-butanediol, is an amino alcohol, which is commonly used in solution phase peptide synthesis.

Application

L-Threoninol can be used as artificial abasic nucleoside in the synthesis and modification of oligodeoxynucleotide and can also be utilized to synthesize pyrene-L-threoninyl analogues.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Synthesis and properties of an oligonucleotide modified with an acridine derivative at the artificial abasic site
K Fukui
Bioconjugate Chemistry, 7, 349-355 (1996)
Potent triple helix stabilization by 5?, 3?-modified triplex-forming oligonucleotides
N Ben Gaied
Chembiochem, 10, 1839-1851 (2009)

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