All Photos(3)
Synonym(s):
1,2-Bis(2-mercaptoethoxy)ethane, 3,6-Dioxa-1,8-octane-dithiol
Linear Formula:
HSCH2CH2OCH2CH2OCH2CH2SH
CAS Number:
Molecular Weight:
182.30
Beilstein:
1901671
EC Number:
MDL number:
UNSPSC Code:
12352103
PubChem Substance ID:
NACRES:
NA.23
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Quality Level
Assay
95%
refractive index
n20/D 1.509 (lit.)
bp
225 °C (lit.)
density
1.12 g/mL at 25 °C (lit.)
SMILES string
SCCOCCOCCS
InChI
1S/C6H14O2S2/c9-5-3-7-1-2-8-4-6-10/h9-10H,1-6H2
InChI key
HCZMHWVFVZAHCR-UHFFFAOYSA-N
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General description
2,2′-(Ethylenedioxy)diethanethiol (EDT) is a dithiol based cross-linker that can be used for thiolene photopolymerization and to obtain crosslinked polymeric films.
3,6-dioxa-1,8-octanedithiol is non volatile in nature.
Application
3,6-dioxa-1,8-octanedithiol (DODT) was used for cleaving peptides in the study to develop synthetic peptide serology to treat chronic chagas disease. DODT may be used to develop non-malodorous scavenger in Fmoc-based peptide synthesis.
EDT can be crosslinked with unsaturated olive oil to form a photoinduced eco-friendly film through renewable sources. It can be used in the synthesis of bioanode for the fabrication of a biofuel cell (BFC) for glucose sensing application. It may also be used for other applications such as improving the optical properties of gold nanoclusters (AuNCs) and the development of bio-mediated synthetic polyester.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Aquatic Acute 1 - Aquatic Chronic 1
WGK
WGK 2
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Renewable Photopolymer Films Derived From Low-Grade Lampante and Pomace Olive Oils.
Khaled B, et al.
European Journal of Lipid Science and Technology, 119(12), 1700003-1700003 (2017)
Crosslinkable polyesters based on monomers derived from renewable lignin.
Zhang J, et al.
Royal Society of Chemistry Advances, 6(14), 11848-11854 (2016)
Insights into the effect of surface ligands on the optical properties of thiolated Au 25 nanoclusters.
Yuan X, et al.
Chemical Communications (Cambridge, England), 52(30), 5234-5237 (2016)
Marco Cavaco et al.
Frontiers in bioengineering and biotechnology, 8, 552035-552035 (2020-10-06)
The characterization of biologically active peptides relies heavily on the study of their efficacy, toxicity, mechanism of action, cellular uptake, or intracellular location, using both in vitro and in vivo studies. These studies frequently depend on the use of fluorescence-based
Andrea D'Ambrogio et al.
Nucleic acids research, 37(12), 4116-4126 (2009-05-12)
Nuclear factor TDP-43 has been reported to play multiple roles in transcription, pre-mRNA splicing, mRNA stability and mRNA transport. From a structural point of view, TDP-43 is a member of the hnRNP protein family whose structure includes two RRM domains
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