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454427

Sigma-Aldrich

Methyldiphenylphosphine oxide

98%

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Synonym(s):
Diphenylmethylphosphine oxide, Methyldiphenyloxophosphine, NSC 407134
Linear Formula:
CH3P(C6H5)2(O)
CAS Number:
Molecular Weight:
216.22
EC Number:
MDL number:
UNSPSC Code:
12352002
PubChem Substance ID:
NACRES:
NA.22

Assay

98%

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: ligand

mp

111-115 °C (lit.)

functional group

phosphine

SMILES string

CP(=O)(c1ccccc1)c2ccccc2

InChI

1S/C13H13OP/c1-15(14,12-8-4-2-5-9-12)13-10-6-3-7-11-13/h2-11H,1H3

InChI key

PEGCITODQASXKH-UHFFFAOYSA-N

Application

Catalyst for:
  • Chlorination and bromination (halogenation) of alcohols under Appel conditions
  • Hydrosilylation reactions
  • Enantioselective cyanosilylation of ketones

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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