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Sigma-Aldrich

D-Glucose-1,6-13C2

≥99 atom % 13C, ≥99% (CP)

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Synonym(s):
Labeled Glucose, Dextrose-1,6-13C2
Empirical Formula (Hill Notation):
13C2C4H12O6
CAS Number:
287100-67-8
Molecular Weight:
182.14
UNSPSC Code:
12352200
PubChem Substance ID:
24868768
NACRES:
NA.12

isotopic purity

≥99 atom % 13C

Quality Level

200

Assay

≥99% (CP)

form

powder

optical activity

[α]25/D +52.0°, c = 2 in H2O (trace NH4OH)

mp

150-152 °C

mass shift

M+2

SMILES string

O[13CH2][C@@H]1O[13CH2][C@@H](O)[C@H](O)[C@H]1O.O

InChI

1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h1,3-6,8-12H,2H2/t3-,4+,5+,6+/m0/s1/i1+1,2+1

InChI key

GZCGUPFRVQAUEE-OFAMVBKFSA-N

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Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Xuemei Tong et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(51), 21660-21665 (2009-12-10)
Tumor cells are metabolically reprogrammed to fuel cell proliferation. Most transformed cells take up high levels of glucose and produce ATP through aerobic glycolysis. In cells exhibiting aerobic glycolysis, a significant fraction of glucose carbon is also directed into de
Ralph J DeBerardinis et al.
Proceedings of the National Academy of Sciences of the United States of America, 104(49), 19345-19350 (2007-11-23)
Tumor cell proliferation requires rapid synthesis of macromolecules including lipids, proteins, and nucleotides. Many tumor cells exhibit rapid glucose consumption, with most of the glucose-derived carbon being secreted as lactate despite abundant oxygen availability (the Warburg effect). Here, we used
Tigran V Yuzbashev et al.
Biotechnology and bioengineering, 113(11), 2425-2432 (2016-05-18)
Bio-based succinic acid production can redirect industrial chemistry processes from using limited hydrocarbons to renewable carbohydrates. A fermentation process that does not require pH-titrating agents will be advantageous to the industry. Previously, a Yarrowia lipolytica strain that was defective for
Barrett L Updegraff et al.
Cell reports, 25(8), 2223-2233 (2018-11-22)
Pathways underlying metabolic reprogramming in cancer remain incompletely understood. We identify the transmembrane serine protease TMPRSS11B as a gene that promotes transformation of immortalized human bronchial epithelial cells (HBECs). TMPRSS11B is upregulated in human lung squamous cell carcinomas (LSCCs), and high

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