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Sigma-Aldrich

D-Glucose-1,2-13C2

99 atom % 13C

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Synonym(s):
Labeled Glucose, Dextrose-1,2-13C2
Empirical Formula (Hill Notation):
13C2C4H12O6
CAS Number:
138079-87-5
Molecular Weight:
182.14
MDL number:
MFCD00144080
UNSPSC Code:
12352200
PubChem Substance ID:
24868766
NACRES:
NA.12

isotopic purity

99 atom % 13C

Quality Level

200

Assay

99% (CP)

form

powder

optical activity

[α]25/D +52.0°, c = 2 in H2O (trace NH4OH)

mp

150-152 °C (lit.)

mass shift

M+2

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)[13C@@H](O)[13CH]=O

InChI

1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h1,3-6,8-12H,2H2/t3-,4+,5+,6+/m0/s1/i1+1,3+1

InChI key

GZCGUPFRVQAUEE-SZEFTZBMSA-N

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Application

D-Glucose-1,2-13C2 can be used:
  • As a stable isotope in the in vivo study of dynamic metabolic profiling of pancreatic tumor.
  • To study the nonoxidative pentose phosphate pathway using a single-tracer method.

Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Mass isotopomer study of the nonoxidative pathways of the pentose cycle with [1, 2-13C2] glucose
Lee, WP, et al.
American Journal of Physiology. Endocrinology and Metabolism, 274(5), E843-E851 (1998)
[1, 2-13C2]-D-glucose profiles of the serum, liver, pancreas, and DMBA-induced pancreatic tumors of rats
Boros L, et al.
Pancreas, 31(4), 337-343 (2005)
Joanna L Gillis et al.
eLife, 10 (2021-08-13)
Alterations to the androgen receptor (AR) signalling axis and cellular metabolism are hallmarks of prostate cancer. This study provides insight into both hallmarks by uncovering a novel link between AR and the pentose phosphate pathway (PPP). Specifically, we identify 6-phosphogluoconate

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