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Sigma-Aldrich

11-Mercaptoundecanoic acid

95%

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Synonym(s):
MUA, MUDA
Linear Formula:
HS(CH2)10CO2H
CAS Number:
71310-21-9
Molecular Weight:
218.36
MDL number:
MFCD00022096
UNSPSC Code:
12352103
PubChem Substance ID:
24868253
NACRES:
NA.23

Assay

95%

form

solid

mp

46-50 °C (lit.)

SMILES string

OC(=O)CCCCCCCCCCS

InChI

1S/C11H22O2S/c12-11(13)9-7-5-3-1-2-4-6-8-10-14/h14H,1-10H2,(H,12,13)

InChI key

GWOLZNVIRIHJHB-UHFFFAOYSA-N

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General description

11-Mercaptoundecanoic acid (MUA) is used as a self-assembled monolayer (SAM) which has a long alkane chain and carboxyl containing thiols. MUA is highly packed and has self-organized surface monolayers. It is a pH responsive ligand which facilitates the dispersion of nanoparticles into water and solvent based media.

Application

MUA as a self-assembled monolayer (SAM) is used as a microfluidic integrated surface plasmon resonance (SPR) for detection and quantification of bacteria in medical diagnostics. It is also used to bio-functionalize the screen printed gold electrodes (SPGEs) that are used for the detection and quantification of dengue. It also forms monolayers on gold nanoparticles (AuNPs) attached via thiol groups. MUA incorporated AuNPs exhibit excellent fluorescence properties which may be used for metal ion detection in serum samples.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

No data available

Flash Point(C)

No data available

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Portable microfluidic integrated plasmonic platform for pathogen detection.
Tokel O, et al.
Scientific Reports, 5(5), 9152-9152 (2015)
Alexey Ivanov et al.
Talanta, 194, 723-730 (2019-01-06)
Reversible inhibitors of acetylcholinesterase are increasingly applied in the Alzheimer's disease therapy. Their determination with biosensors requires special attention to the enzyme immobilization due to importance of electrostatic and steric factors affecting accessibility of the active site to the substrate
Electrochemical lateral flow immunosensor for detection and quantification of dengue NS1 protein.
Sinawang PD, et al.
Biosensors And Bioelectronics, 77(5), 400-408 (2016)
Li Han et al.
Langmuir : the ACS journal of surfaces and colloids, 20(14), 6019-6025 (2006-02-08)
The preparation of nanocomposite materials from carbon nanotubes (CNTs) and metal or metal oxide nanoparticles has important implications to the development of advanced catalytic and sensory materials. This paper reports findings of an investigation of the preparation of nanoparticle-coated carbon
11-Mercaptoundecanoic acid functionalized gold nanoclusters as fluorescent probes for the sensitive detection of Cu2+ and Fe3+ ions.
Bai Z, et al.
Chinese Chemical Letters = Zhongguo Hua Xue Kuai Bao, 28(9), 1901-1904 (2017)
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