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450243

Sigma-Aldrich

Sodium orthovanadate

99.98% trace metals basis

Synonym(s):

Trisodium vanadate

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About This Item

Linear Formula:
Na3VO4
CAS Number:
13721-39-6
Molecular Weight:
183.91
EC Number:
237-287-9
MDL number:
MFCD00003511
UNSPSC Code:
12161600
PubChem Substance ID:
24868233
NACRES:
NA.22

Quality Level

200

Assay

99.98% trace metals basis

form

solid

reaction suitability

core: vanadium
reagent type: catalyst

mp

850-866 °C (lit.)

SMILES string

[Na+].[Na+].[Na+].[O-][V]([O-])([O-])=O

InChI

1S/3Na.4O.V/q3*+1;;3*-1;

InChI key

IHIXIJGXTJIKRB-UHFFFAOYSA-N

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Application

Sodium orthovanadate (Na3VO4) can be used as a metal precursor in the synthesis of:
  • Vanadium-MCM-48 (V-MCM-48) by anion-exchange method. V-MCM-48 is used as a catalyst in oxidation of styrene to benzaldehyde.
  • Nanorods of vanadium oxide particles by glycothermal method.
  • Yttrium vanadate (YVO4) doped with colloidal europium.

Biochem/physiol Actions

An inhibitor of protein tyrosine phosphatases, alkaline phosphatases and ATPases.
Inhibits ATPase, alkaline phosphatase and tyrosine phosphatase. Decavanadate, which is formed at acidic pH, inhibits inositol 1,4,5-trisphosphate (IP3)-induced Ca2+ release from endocrine cells and blocks IP3 binding to its receptor in brain tissue.

Packaging

Exhibits various biological and physiological effects in the human body

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. What is the solubility of Product 450243, sodium orthovandate, and how do I store the solution?

    Solutions prepared as 1 mM in water (or higher if desired) and adjusted to pH 10 can be aliquotted in plastic tubes and stored at -20°C. To ensure the presence of monomers, solutions should be heated to boiling until translucent and pH re-adjusted to 10.

  4. For Product 450243, Sodium orthovanadate, what does metal basis purity mean?

    This product's purity is determined by ICP analysis. Trace metal impurities are analyzed, quantified and reported on the certificate of analysis for each lot/batch of product. The total metallic impurities are subtracted from 100% to result in the purity percentage based on metals.

  5. What is Product 450243, Sodium orthovanadate, typically used for?

    This product can be used as a catalyst in chemical synthesis. It also utilized as an inhibitor of ATPase, alkaline phosphatase and tyrosine phosphatase.

  6. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  7. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

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    Ask a Scientist here.

Synthesis and characterization of TM-MCM-48 (TM= Mn, V, Cr) and their catalytic activity in the oxidation of styrene.
Gomez S, et al.
J. Catal., 233(1), 60-67 (2005)
Synthesis and characterizations of YVO4: Eu colloids.
Huignard A, et al.
Chemistry of Materials, 14(5), 2264-2269 (2002)
Glycothermal synthesis of assembled vanadium oxide nanostructures for gas sensing.
Fu H, et al.
Journal of Nanoparticle Research, 14(6), 871-871 (2012)
Yu Hasegawa et al.
The Journal of pharmacology and experimental therapeutics, 317(2), 875-881 (2006-02-08)
Vanadium is widely distributed in the environment and exhibits various biological and physiological effects in the human body. We previously documented the neuroprotective effect of sodium orthovanadate (SOV) against in rodents i.v. injected with 2 ml/kg 50 mM SOV just
A Morita et al.
Cell death and differentiation, 13(3), 499-511 (2005-09-03)
We previously reported that p42/SETbeta is a substrate for caspase-7 in irradiated MOLT-4 cells, and that treating the cells with sodium orthovanadate (vanadate) inhibits p42/SETbeta's caspase-mediated cleavage. Here, we initially found that the inhibitory effect of vanadate was due to
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