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445495

Sigma-Aldrich

Maleamic acid

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Linear Formula:
H2NCOCH=CHCO2H
CAS Number:
Molecular Weight:
115.09
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

form

solid

Quality Level

mp

158-161 °C (lit.)

SMILES string

[H]\C(=C(/[H])C(O)=O)C(N)=O

InChI

1S/C4H5NO3/c5-3(6)1-2-4(7)8/h1-2H,(H2,5,6)(H,7,8)/b2-1-

InChI key

FSQQTNAZHBEJLS-UPHRSURJSA-N

Related Categories

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Juan Rodrigues et al.
Pharmaceutical research, 28(4), 907-919 (2010-12-25)
The objective of this study was to investigate the effect of new 4-maleamic acid and 4-maleamide peptidyl chalcone derivatives against human prostate cancer in vitro and in vivo. From a series of 21 chalcones, the effects of the three best
Meifang Huang et al.
International journal of biological macromolecules, 36(1-2), 98-102 (2005-06-14)
N-maleamic acid-chitosan was synthesized and characterized by Fourier transform infrared spectra analysis (FT-IR) and 1H NMR. The graft copolymerization of N-maleamic acid-chitosan and butyl acrylate (BA) in acetic acid aqueous solution was investigated, using the gamma-ray of 60Co gamma-irradiation method.
Maleamic and citraconamic acids, methyl esters, and imides.
MEHTA NB, et al.
The Journal of Organic Chemistry, 25(6), 1012-1015 (1960)
Yoshihiro Miyaji et al.
Pharmaceutical research, 29(11), 3143-3155 (2012-06-26)
Recombinant osteoprotegerin (OPG) has been proven to be useful for treating various bone disorders such as osteoporosis. To improve its in vivo pharmacological effect, OPG was conjugated to novel comb-shaped co-polymers of polyethylene glycol (PEG) allylmethylether and maleamic acid (poly(PEG)
C V Vassena et al.
Journal of medical entomology, 33(5), 823-827 (1996-09-01)
We found that feeding behavior of Triatoma infestans (Klug) 5th-instar nymphs was blocked by topical application of the cis-isomers of methyl esters of N-substituted maleamic acids, synthesized in our laboratory. The antifeeding effect of these compounds was determined by exposing

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