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Merck
CN

426008

Carbofuran

98%

Synonym(s):

2,3-Dihydro-2,2-dimethyl-7-benzofuranol N-methylcarbamate

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About This Item

Empirical Formula (Hill Notation):
C12H15NO3
CAS Number:
1563-66-2
Molecular Weight:
221.25
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
24866678
EC Number:
216-353-0
Beilstein/REAXYS Number:
1428746
MDL number:
MFCD00041819

Key Documents

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Product Name

Carbofuran, 98%

InChI key

DUEPRVBVGDRKAG-UHFFFAOYSA-N

InChI

1S/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)

SMILES string

CNC(=O)Oc1cccc2CC(C)(C)Oc12

assay

98%

form

crystals

mp

150-153 °C (lit.)

functional group

amine

Quality Level

100

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General description

Carbofuran is an anticholinesterase carbamate, which is commonly used as a pesticide. Its literature data on toxicity have been reviewed. The effect from exposure to carbofuran has been investigated on acetylcholinesterase (AChE) activity in the brain and muscle of common carp (Cyprinus carpio). Degradation studies using ozone, UV radiation and advanced oxidation processes (AOPs) and by photocatalytic degradation have been investigated. Ultra high performance liquid chromatography (UHPLC) method to determine the carbofuran in water samples have been developed with satisfactory results.

pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

Hazard Classifications

Acute Tox. 1 Oral - Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
MKCZ5488
MKCX4322
MKCW0953
MKCT1015
MKCQ8959

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Degradation of carbofuran by using ozone, UV radiation and advanced oxidation processes.
Benitez FJ, et al.
Journal of Hazardous Materials, 89(1), 51-65 (2002)
Photocatalytic degradation of carbofuran using semiconductor oxides.
Mahalakshmi M, et al.
Journal of Hazardous Materials, 143(1), 240-245 (2007)
Kun Jia et al.
Ecotoxicology and environmental safety, 96, 61-66 (2013-07-23)
The effects of carbofuran toxicity on a genetically modified bacterial strain E. coli DPD2794 were enhanced using a new bioluminescent protocol which consisted of three consecutive steps: incubation, washing and luminescence reading. Specifically, in the first step, several concentrations of
Anna Lundqvist et al.
Ecotoxicology (London, England), 21(8), 2398-2408 (2012-09-08)
We studied the fate and bioavailability of insecticides in short-term experiments (48 h) with different hydrophobicity (3.8 pM carbofuran, 3.0 pM lindane, and 5.3 pM chlorpyrifos) across gradients in dissolved organic matter (low-, medium-, and high-DOM) in freshwater microcosms, mimicking
Divya Mishra et al.
Toxicological sciences : an official journal of the Society of Toxicology, 127(1), 84-100 (2012-01-14)
Neurogenesis is a process of generation of new neurons in the hippocampus and associated with learning and memory. Carbofuran, a carbamate pesticide, elicits several neurochemical, neurophysiological, and neurobehavioral deficits. We evaluated whether chronic prenatal oral exposure of carbofuran during gestational
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