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Sigma-Aldrich

Bis(hexamethylene)triamine

high purity

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Synonym(s):
6,6′-Iminodihexylamine, Bis(6-aminohexyl)amine
Linear Formula:
NH2(CH2)6NH(CH2)6NH2
CAS Number:
143-23-7
Molecular Weight:
215.38
Beilstein:
2323517
EC Number:
205-593-1
MDL number:
MFCD00010448
UNSPSC Code:
12352100
PubChem Substance ID:
24866405
NACRES:
NA.22

vapor pressure

<0.01 mmHg ( 25 °C)

form

solid

refractive index

n20/D 1.49 (lit.)

bp

163-165 °C/4 mmHg (lit.)

mp

33-36 °C (lit.)

density

0.85 g/mL at 20 °C (lit.)
0.879 g/mL at 25 °C

SMILES string

NCCCCCCNCCCCCCN

InChI

1S/C12H29N3/c13-9-5-1-3-7-11-15-12-8-4-2-6-10-14/h15H,1-14H2

InChI key

MRNZSTMRDWRNNR-UHFFFAOYSA-N

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General description

Bis(hexamethylene)triamine (Bis-HEA, BHMT, BHMTA) is an aliphatic polyamine. It is a spermidine analog and has been reported to lack the enhancing effect on mitochondrial Ca(2+) accumulation but shows inhibitory effect on the Ca(2+) and Pi-induced mitochondrial permeability transition. Its ability in inhibiting shale swelling and dispersion in water-based drilling fluid has been investigated.

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 1

Flash Point(F)

closed cup

Flash Point(C)

closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Interior synthesizing of ZnO nanoflakes inside nylon-6 electrospun nanofibers.
Panthi G, et al.
Journal of Applied Polymer Science, 127(3), 2025-2032 (2013)
Antibacterial and photocatalytic properties of Ag/TiO2/ZnO nano-flowers prepared by facile one-pot hydrothermal process.
Pant HR, et al.
Ceramics International, 39(2), 1503-1510 (2013)
Co3O4-ZnO hierarchical nanostructures by electrospinning and hydrothermal methods.
Kanjwal MA, et al.
Applied Surface Science, 257(18), 7975-7981 (2011)
Bis (hexamethylene) triamine as potential shale inhibitor in water-based drilling fluid.
Zhong H, et al.
Open Petroleum Engineering Journal, 6, 49-56 (2013)
I Rustenbeck et al.
Biochemistry and molecular biology international, 38(5), 1003-1011 (1996-04-01)
The aliphatic polyamine bis(hexamethylene)triamine, a spermidine analogue, was found to lack the enhancing effect on mitochondrial Ca(2+) accumulation which is typical for the natural polyamines, spermidine and spermine. However, like spermine and spermidine, this compound had a significant inhibitory effect
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