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Merck
CN

420247

(+)-Borneol

97%

Synonym(s):

endo-(1R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol

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About This Item

Empirical Formula (Hill Notation):
C10H18O
CAS Number:
464-43-7
Molecular Weight:
154.25
UNSPSC Code:
12352212
NACRES:
NA.22
PubChem Substance ID:
24866321
EC Number:
207-352-6
Beilstein/REAXYS Number:
2038056
MDL number:
MFCD00066427

Key Documents

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Product Name

(+)-Borneol, 97%

InChI key

DTGKSKDOIYIVQL-WEDXCCLWSA-N

InChI

1S/C10H18O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7-8,11H,4-6H2,1-3H3/t7-,8+,10+/m1/s1

SMILES string

[H][C@@]12CC[C@@](C)([C@@H](O)C1)C2(C)C

assay

97%

form

solid

optical activity

[α]20/D +36°, c = 5 in ethanol

mp

206-209 °C (lit.)

functional group

hydroxyl

Quality Level

200

Gene Information

human ... UGT1A4(54657)

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Application

(+)-Borneol has been used to study its antiapoptotic, antioxidative and neuroprotective effect in human neuroblastoma cells (SH-SY5Y).

General description

(+)-Borneol, a bicyclic monoterpene, is found in the essential oils of medicinal plants and is commonly used in traditional Chinese medicine for analgesia and anaesthesia.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

Flame
GHS02

signalword

Warning

hcodes

H228

Hazard Classifications

Flam. Sol. 2

Storage Class

4.1B - Flammable solid hazardous materials

wgk

WGK 3

flash_point_f

149.0 °F - closed cup

flash_point_c

65 °C - closed cup

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

危险化学品
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Certificates of Analysis (COA)

Lot/Batch Number
0000506330
0000506330
0000479716
0000479716
0000204322

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Borneol alleviates oxidative stress via upregulation of Nrf2 and Bcl-2 in SH-SY5Y cells.
Hur J, et al.
Pharmaceutical Analysis, 51(1), 30-35 (2013)
(+)-And (-)-borneol: efficacious positive modulators of GABA action at human recombinant a 1 ? 2 ? 2L GABA A receptors.
Granger RE, et al.
Biochemical Pharmacology, 69(7), 1101-1111 (2005)
Liang Zou et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(22), 3490-3493 (2013-02-05)
To explore the influence of borneol on intestinal absorption of muscone in rats. An in situ intestinal circulation perfusion experiment was used to study the changes in intestinal absorption kinetics of muscone before and after being compatible with borneol. Compared
Wan Ren-Zhong et al.
Journal of Asian natural products research, 14(6), 538-544 (2012-05-17)
The main purpose of this study was to illustrate the effect of borneol on pharmacokinetics of salvianolic acid B (SalB) in rats after oral administration of SalB with different doses of borneol. The concentrations of SalB in rat plasma were
Jianyu Su et al.
Journal of food science, 77(6), C658-C664 (2012-05-16)
The aims of this study were to optimize the preparation conditions of natural borneol/β-cyclodextrin (NB/β-CD) inclusion complex by ultrasound method, and to investigate its improvement of stability and solubility. The complex was characterized by different various spectroscopic techniques including Fourier
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