Skip to Content
Merck
CN
All Photos(1)

Key Documents

View All Documentation

Safety Information

420107

Sigma-Aldrich

Bromotris(dimethylamino)phosphonium hexafluorophosphate

98%

Synonym(s):

BroP, Bromotris(N-methylmethanaminato)-phosphorus hexafluorophosphate

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
BrP[N(CH3)2]3PF6
CAS Number:
50296-37-2
Molecular Weight:
388.07
MDL number:
MFCD00191864
UNSPSC Code:
12352101
PubChem Substance ID:
24866311

Assay

98%

reaction suitability

reaction type: Coupling Reactions

mp

>300 °C (lit.)

application(s)

peptide synthesis

SMILES string

F[P-](F)(F)(F)(F)F.CN(C)[P+](Br)(N(C)C)N(C)C

InChI

1S/C6H18BrN3P.F6P/c1-8(2)11(7,9(3)4)10(5)6;1-7(2,3,4,5)6/h1-6H3;/q+1;-1

InChI key

XELPBWPBGHCIKX-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

Reagent for:
Conjugate addition of nitroalkanes to an acrylate equivalent
A novel polymer supported approach to nucleoside modification
Asymmetric hydrogenations
Peptide coupling
Pyrrolidine hydroxylation
Synthesis of cyclic PNA-based compound directed against HIV-1 TAR RNA

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Pictograms

Health hazardCorrosion
GHS08,GHS05

Signal Word

Danger

Hazard Statements

H314,H350

Hazard Classifications

Carc. 1B - Skin Corr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

新产品

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
011821/4V
1452305V
1452305
011821/4
09810TC

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

A M Senderowicz et al.
Journal of the National Cancer Institute, 87(1), 46-51 (1995-01-04)
Jasplakinolide, a cyclodepsipeptide produced by an Indo-Pacific sponge, Jaspis johnstoni, has been reported to inhibit the growth of breast cancer cells. The effects of jasplakinolide on the proliferation of three human immortalized prostate carcinoma cell lines (PC-3, LNCaP, and TSU-Pr1)
J A Rosado et al.
The Journal of biological chemistry, 275(11), 7527-7533 (2000-03-14)
The nature of the mechanism underlying store-mediated Ca(2+) entry has been investigated in human platelets through a combination of cytoskeletal modifications. Inhibition of actin polymerization by cytochalasin D or latrunculin A had a biphasic time-dependent effect on Ca(2+) entry, showing
Zizhuo Su et al.
Journal of vascular research, 57(5), 254-260 (2020-06-12)
The exocytosis of cyclophilin A (CyPA) by a vesicular pathway in response to reactive oxygen species has been determined. However, other sources of extracellular CyPA remain obscure. The aim of this study was to determine the role of autophagy in
M R Bubb et al.
The Journal of biological chemistry, 269(21), 14869-14871 (1994-05-27)
Jasplakinolide, a naturally occurring cyclic peptide from the marine sponge, Jaspis johnstoni, has both fungicidal and antiproliferative activity. We now report that this peptide is a potent inducer of actin polymerization in vitro. The peptide has a much greater effect
V R Scott et al.
Antimicrobial agents and chemotherapy, 32(8), 1154-1157 (1988-08-01)
Jasplakinolide is a cyclodepsipeptide which represents a new class of antifungal agents with potent activity against Candida albicans. Jasplakinolide is fungicidal against C. albicans with both a MIC and a minimum lethal concentration of 25 micrograms/ml in a broth dilution
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service