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419419

Sigma-Aldrich

Chitosan

high molecular weight

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Synonym(s):
Deacetylated chitin, Poly(D-glucosamine)
CAS Number:
9012-76-4
MDL number:
MFCD00161512
UNSPSC Code:
12352201
NACRES:
NA.23

Quality Level

100

form

(Coarse ground flakes and powder)

mol wt

310000-375000 Da

viscosity

800-2000 cP, 1 wt. % in 1% acetic acid(25 °C, Brookfield)(lit.)

solubility

H2O: insoluble
organic solvents: insoluble

InChI

1S/C56H103N9O39/c1-87-56(86)65-28-38(84)46(19(10-74)96-55(28)104-45-18(9-73)95-49(27(64)37(45)83)97-39-12(3-67)88-47(85)20(57)31(39)77)103-54-26(63)36(82)44(17(8-72)94-54)102-53-25(62)35(81)43(16(7-71)93-53)101-52-24(61)34(80)42(15(6-70)92-52)100-51-23(60)33(79)41(14(5-69)91-51)99-50-22(59)32(78)40(13(4-68)90-50)98-48-21(58)30(76)29(75)11(2-66)89-48/h11-55,66-85H,2-10,57-64H2,1H3,(H,65,86)/t11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48+,49+,50+,51+,52+,53+,54+,55+/m1/s1

InChI key

FLASNYPZGWUPSU-SICDJOISSA-N

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Application

Forms gels with multivalent anions. Gives clear solutions that dry to strong, clear films.

Features and Benefits

Biocompatible, antibacterial and environmentally friendly polyelectrolyte with a variety of applications including water treatment, chromatography, additives for cosmetics, textile treatment for antimicrobial activity, novel fibers for textiles, photographic papers, biodegradable films, biomedical devices, and microcapsule implants for controlled release in drug delivery.

Physical form

>75% deacetylated

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. What is the molecular weight of Chitosan, Product 419419?

    Although we do not measure molecular weight on a batch to batch basis, we would expect it to be approximately 310,000 to >375,000 based on the viscosity range of 800-2000 mPaS.

  4. What is the particle size of Product 419419, Chitosan?

    The particle size has not been determined.  It is described as being course ground flakes or powder.

  5. What is the solubility of Product 419419, Chitosan?

    Chitosan is insoluble in water or organic solvents.  Hazy suspensions can be prepared in 1M acetic acid at a concentration of 10 mg/mL, but extensive sonication may be required to fully suspend the material.

  6. What is the source of Product 419419, Chitosan?

    Chitosan is a natural biopolymer commerically derived from chitin from crustacean shells.  

  7. What is the pH of Product 419419, Chitosan?

    Our supplier estimates that the pH falls within the range of 6.5-8.0.

  8. What are some uses for chitosan?

    Chitosan is a biocompatible, antibacterial and environmentally friendly polyelectrolyte with a variety of applications including water treatment, chromatography, additives for cosmetics, textile treatment for antimicrobial activity, novel fibers for textiles, photographic papers, biodegradable films, biomedical devices, and microcapsule implants for controlled release in drug delivery. Please note that Product No. 419419 is for research purposes only, not for cosmetic or drug use.

  9. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  10. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  11. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Thomas M Higgins et al.
Nanomaterials (Basel, Switzerland), 1(1), 3-19 (2011-04-06)
The mechanical and electrical characteristics of films, buckypapers and fiber materials from combinations of clay, carbon nanotubes (CNTs) and chitosan are described. The rheological time-dependent characteristics of clay are maintained in clay-carbon nanotube-chitosan composite dispersions. It is demonstrated that the
Jianjun Miao et al.
Langmuir : the ACS journal of surfaces and colloids, 28(9), 4396-4403 (2012-02-09)
Extracorporeal filter cartridges, filled with an activated carbon bead (ACB) adsorbent, have been used for removal of overdosed cancer drugs from the blood. Coatings on adsorbent matrices, poly(methyl methacrylate) (PMMA)/activated carbon bead and PMMA/chitosan/heparin/ACB composites, were tested to improve their
Javiera F Rubilar et al.
International journal of biological macromolecules, 104(Pt A), 197-203 (2017-06-08)
Controlled release of antimicrobial and antioxidant compounds from packaging films is of utmost importance for extending the shelf-life of perishable foods. This study focused on the mathematical modeling of gallic acid release into an aqueous medium from three chitosan films
A D Anastasiou et al.
Acta biomaterialia, 71, 86-95 (2018-02-21)
A radical new methodology for the exogenous mineralization of hard tissues is demonstrated in the context of laser-biomaterials interaction. The proposed approach is based on the use of femtosecond pulsed lasers (fs) and Fe3+-doped calcium phosphate minerals (specifically in this
Antonia G Moutzouri et al.
BioMed research international, 2014, 740726-740726 (2014-07-06)
Cell adhesion on substrates is accompanied by significant changes in shape and cytoskeleton organization, which affect subsequent cellular and tissue responses, determining the long-term success of an implant. Alterations in osteoblast stiffness upon adhesion on orthopaedic implants with different surface
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