All Photos(1)
Linear Formula:
C6H5CH2COCF3
CAS Number:
Molecular Weight:
188.15
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
Quality Level
Assay
96%
form
liquid
refractive index
n20/D 1.444 (lit.)
bp
51-52 °C/2 mmHg (lit.)
density
1.22 g/mL at 25 °C (lit.)
SMILES string
FC(F)(F)C(=O)Cc1ccccc1
InChI
1S/C9H7F3O/c10-9(11,12)8(13)6-7-4-2-1-3-5-7/h1-5H,6H2
InChI key
IAJKTOIWQHTZOS-UHFFFAOYSA-N
Related Categories
General description
1,1,1-Trifluoro-3-phenyl-2-propanone is a trifluoromethyl ketone. Its in vitro neuroprotective potency against low K(+)-induced apoptosis in cerebellar granule neurons (CGNs) by different pathways has been reported.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Flam. Liq. 3
WGK
WGK 3
Flash Point(F)
91.4 °F
Flash Point(C)
33 °C
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Katsuyoshi Sunaga et al.
In vivo (Athens, Greece), 16(2), 97-101 (2002-06-21)
We previously reported that two trifluoromethyl ketones, 3,3,3-trifluoro-1-phenyl-1,2-propanedione (TF1) and 1,1,1-trifluoro-3-phenyl-2-propanone (TF2), have neuroprotective effects against low K(+)-induced apoptosis in cerebellar granule neurons (CGNs) exposed at 12-13 days in vitro (DIV). On the other hand, these compounds showed weak neuroprotective
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