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412252

Sigma-Aldrich

(Ethoxycarbonylmethyl)triphenylphosphonium bromide

98%

Synonym(s):

(Carboxymethyl)triphenylphosphonium bromide ethyl ester, NSC 60450

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About This Item

Linear Formula:
CH3CH2OCOCH2P(C6H5)3Br
CAS Number:
Molecular Weight:
429.29
Beilstein:
3581273
EC Number:
MDL number:
UNSPSC Code:
12352108
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

98%

reaction suitability

reaction type: C-C Bond Formation

mp

145-150 °C (dec.) (lit.)

SMILES string

[Br-].CCOC(=O)C[P+](c1ccccc1)(c2ccccc2)c3ccccc3

InChI

1S/C22H22O2P.BrH/c1-2-24-22(23)18-25(19-12-6-3-7-13-19,20-14-8-4-9-15-20)21-16-10-5-11-17-21;/h3-17H,2,18H2,1H3;1H/q+1;/p-1

InChI key

VJVZPTPOYCJFNI-UHFFFAOYSA-M

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Application

Reactant for:
  • Wittig olefination reactions for synthesis of tetramic acid derivatives
  • Synthesis of precursors for Bergman cyclization
  • Preparation of PPAR agonists derived from thalidomide-related LXR antagonists
  • Synthesis of benzoxaboroles with antimalarial activity
  • Michael acceptor based cysteine protease inhibitors
  • Mechanistic studies of the IspH reductase protein

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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