412201
L-Serine methyl ester hydrochloride
98%, for peptide synthesis
Synonym(s):
L-Serine methyl ester·HCl
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About This Item
Linear Formula:
HOCH2CH(NH2)COOCH3 · HCl
CAS Number:
Molecular Weight:
155.58
NACRES:
NA.22
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
227-140-7
MDL number:
Beilstein/REAXYS Number:
3559591
Product Name
L-Serine methyl ester hydrochloride, 98%
InChI key
NDBQJIBNNUJNHA-DFWYDOINSA-N
InChI
1S/C4H9NO3.ClH/c1-8-4(7)3(5)2-6;/h3,6H,2,5H2,1H3;1H/t3-;/m0./s1
SMILES string
Cl.COC(=O)[C@@H](N)CO
assay
98%
form
powder
optical activity
[α]20/D +3.4°, c = 4 in methanol
reaction suitability
reaction type: solution phase peptide synthesis
mp
163 °C (dec.) (lit.)
application(s)
peptide synthesis
Quality Level
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Ernest Mordret et al.
Molecular cell, 75(3), 427-441 (2019-07-30)
The translation machinery and the genes it decodes co-evolved to achieve production throughput and accuracy. Nonetheless, translation errors are frequent, and they affect physiology and protein evolution. Mapping translation errors in proteomes and understanding their causes is hindered by lack
J Sélambarom et al.
Carbohydrate research, 330(1), 43-51 (2001-02-24)
The reaction of L-serine methyl ester hydrochloride (1) with paraformaldehyde (2) in dichloromethane in the presence of triethylamine afforded a novel compound: [lS,2S,6S,7S]-1,6-diaza-4,9-dioxa-2,7-dimethoxycarbonylbicyclo[4.4.1]undecane (4) as a 2:3 adduct of 1 with 2. 1H and 13C NMR spectroscopy were unable to
Acylated serine derivatives: a unique class of arthropod pheromones of the Australian redback spider, Latrodectus hasselti.
Elena Jerhot et al.
Angewandte Chemie (International ed. in English), 49(11), 2037-2040 (2010-02-11)
Cédric Couturier et al.
Organic letters, 8(10), 2183-2186 (2006-05-05)
[reaction: see text] Reaction of N,N-dibenzyl-O-methylsulfonyl serine methyl ester with a variety of heteronucleophiles (sodium azide, sodium phthalimide, amines, thiols) and carbanions (sodium malonate) gave, via an aziridinium intermediate, the corresponding beta-amino or alpha,beta-diamino ester in good to excellent yield.
Chih-Sheng Yang et al.
EMBO reports, 19(6) (2018-04-18)
The transcriptional regulators TAZ and YAP (TAZ/YAP) have emerged as pro-tumorigenic factors that drive many oncogenic traits, including induction of cell growth, resistance to cell death, and activation of processes that promote migration and invasion. Here, we report that TAZ/YAP
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