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Merck
CN

405655

2-Hydroxy-2-methylpropiophenone

97%

Synonym(s):

1-Hydroxy-1-methylethyl phenyl ketone, 1-Phenyl-2-methyl-2-hydroxypropanone, 2-Hydroxy-2-methyl-1-phenyl-1-propanone, 2-Methyl-3-phenyl-3-oxopropan-2-ol

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About This Item

Linear Formula:
C6H5COC(CH3)2OH
CAS Number:
7473-98-5
Molecular Weight:
164.20
NACRES:
NA.23
PubChem Substance ID:
24865322
UNSPSC Code:
12162002
EC Number:
231-272-0
MDL number:
MFCD00040710

Key Documents

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Product Name

2-Hydroxy-2-methylpropiophenone, 97%

InChI key

XMLYCEVDHLAQEL-UHFFFAOYSA-N

InChI

1S/C10H12O2/c1-10(2,12)9(11)8-6-4-3-5-7-8/h3-7,12H,1-2H3

SMILES string

CC(C)(O)C(=O)c1ccccc1

assay

97%

form

liquid

refractive index

n20/D 1.533 (lit.)

bp

102-103 °C/4 mmHg (lit.)

density

1.077 g/mL at 25 °C (lit.)

Quality Level

200

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Application

  • Photochemical Thiol-Ene “Click” Chemistry: The study utilized 2-hydroxy-2-methylpropiophenone for the synthesis of highly functional polyols by photochemical thiol-ene “click” chemistry (M Ionescu, A Garcia-Comer, T Spidel, 2023).
  • Development of Water-Soluble Type I Photoinitiators: This study focused on the development of new water-soluble type I photoinitiators for hydrogel synthesis using 2-hydroxy-2-methylpropiophenone, enhancing the understanding of photopolymerization processes (B Aubry, F Dumur, M Lansalot, E Bourgeat-Lami, 2022).

General description

2-Hydroxy-2-methylpropiophenone is a radical photoinitiator (PI) molecule that can be used in the crosslinking of polymers by the exposure of UV radiation. It can be used in the development of UV curable resins for exterior coating applications.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302,H412

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

251.6 °F - closed cup

flash_point_c

122 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number
MKCZ9517
0000499839
0000499839
MKCX8496
0000408730

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UV-Radiation curing of waterbased urethane-acrylate coatings
Masson F, et al.
Progress in Organic Coatings, 39(2-4), 115-126 (2000)
Lu Li et al.
Polymers, 12(1) (2020-01-18)
The detection of p-nitrophenol (PNP) is of great significance for assessment of environment pollution and potential health risks. In this study, based on inverse opal polymeric photonic crystals (IOPPCs), a selective and visual sensor for high-performance PNP detection is developed.
Anirudha Banerjee et al.
Science advances, 5(8), eaax1893-eaax1893 (2019-08-28)
Structures and particles that slowly release solute into solution can attract or repel other particles in suspension via diffusiophoresis, a process we termed "soluto-inertial (SI) interactions." These SI interactions involve "beacons" that establish and sustain nonequilibrium solute fluxes over long
Minggan Li et al.
Langmuir : the ACS journal of surfaces and colloids, 33(1), 184-190 (2016-12-10)
A microfluidic flow lithography approach was investigated to synthesize highly porous nonspherical particles and Janus particles in a one-step and high-throughput fashion. In this study, using common solvents as porogens, we were able to synthesize highly porous particles with different
Ana-Irina Cocarta et al.
Materials science & engineering. C, Materials for biological applications, 103, 109799-109799 (2019-07-28)
Retinoblastoma (Rb) is the most common primary malignant intraocular tumor in children which develops from the retinal stem cells. Systemic chemotherapy is the typical therapeutic treatment and though most children survive Rb, they often lose their vision, or the eye
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