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Merck
CN

403245

(3-Carboxypropyl)trimethylammonium chloride

technical grade

Synonym(s):

γ-Butyrobetaine hydrochloride, Deoxycarnitine hydrochloride

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About This Item

Linear Formula:
C7H16NO2Cl
CAS Number:
Molecular Weight:
181.66
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352116
MDL number:
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Product Name

(3-Carboxypropyl)trimethylammonium chloride, technical grade

InChI

1S/C7H15NO2.ClH/c1-8(2,3)6-4-5-7(9)10;/h4-6H2,1-3H3;1H

SMILES string

[Cl-].C[N+](C)(C)CCCC(O)=O

InChI key

GNRKTORAJTTYIW-UHFFFAOYSA-N

grade

technical grade

mp

220 °C (dec.) (lit.)

Quality Level

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Related Categories

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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L M Henderson et al.
Federation proceedings, 41(12), 2843-2847 (1982-10-01)
The biosynthesis of carnitine proceeds from trimethyllysine (TML) by beta-hydroxylation by a liver or kidney mitochondrial enzyme, which requires oxygen, alpha-ketoglutarate, ferrous iron, and ascorbate. This dioxygenase is rapidly inactivated by preincubation with Fe2+, but not Fe3+. The evidence suggests
W J Thoma et al.
Biochimica et biophysica acta, 797(1), 136-139 (1984-01-24)
The effect of ascorbate deficiency on carnitine biosynthesis was investigated in young male guinea pigs. Liver and skeletal muscle carnitine levels were reduced in scorbutic animals. Heart and kidney concentrations remained unchanged. 14C-labeled 4-N-trimethylaminobutyrate was administered to control, pair-fed and
J S Serrano et al.
Methods and findings in experimental and clinical pharmacology, 5(4), 251-254 (1983-01-01)
The effects of GABA, its quaternary derivative N-trimethyl GABA and quinidine have been studied in a model of ventricular automaticity induced in the isolated right ventricle of the rat. GABA shows low anti-automatic activity. N-trimethyl GABA and quinidine were, however
Frédéric M Vaz et al.
The Biochemical journal, 361(Pt 3), 417-429 (2002-01-23)
Carnitine is indispensable for energy metabolism, since it enables activated fatty acids to enter the mitochondria, where they are broken down via beta-oxidation. Carnitine is probably present in all animal species, and in numerous micro-organisms and plants. In mammals, carnitine
P J Nelson et al.
Biochimica et biophysica acta, 672(1), 123-127 (1981-01-07)
The effects of ascorbate deficiency on carnitine biosynthesis was investigated in young male guinea pigs. Liver and kidney carnitine levels were not affected by the deficiency, but scorbutic animals had 50% less carnitine in heart and skeletal muscle than control

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