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Merck
CN

39391

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide

≥97.0% (T), for peptide synthesis

Synonym(s):

N-Ethyl-N′-(3-dimethylaminopropyl)carbodiimide, EDC, WSC

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About This Item

Empirical Formula (Hill Notation):
C8H17N3
CAS Number:
1892-57-5
Molecular Weight:
155.24
NACRES:
NA.22
PubChem Substance ID:
57649895
UNSPSC Code:
12352116
EC Number:
217-579-2
MDL number:
MFCD00044916
Beilstein/REAXYS Number:
507429

Key Documents

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Product Name

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide, ≥97.0% (T)

InChI key

LMDZBCPBFSXMTL-UHFFFAOYSA-N

InChI

1S/C8H17N3/c1-4-9-8-10-6-5-7-11(2)3/h4-7H2,1-3H3

SMILES string

CCN=C=NCCCN(C)C

assay

≥97.0% (T)

form

liquid

reaction suitability

reaction type: Coupling Reactions

density

0.877 g/mL at 20 °C (lit.)

application(s)

peptide synthesis

functional group

amine

storage temp.

−20°C

Quality Level

100

refractive index

n20/D 1.460-1.463

Related Categories

Application

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide has been used for the surface functionalization of graphene quantum dots (GQDs) employed as sensing probes in Janus micromotors to detect enterobacterial contamination. It has also been used for the activation of folic acid, prior to its conjugation on silica nanoparticles.

General description

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide is commonly used in combination with N-hydroxysuccinimide (NHS) in carbodiimide coupling reaction to activate carboxyl group for coupling with amines to form amides.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A - Skin Sens. 1A - STOT RE 2 Oral

target_organs

Stomach,large intestine,lymph node

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN8784
BCCN2214
BCCM2788
BCCK2801
BCCL1199

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